Biotechnology
DiscoveRx(R) Corporation's KINOMEscan Technology Reveals Kinome-Wide Fingerprints Against Diverse Set of Mature Kinase Inhibitors and FDA Approved Therapeutics
Published in Medical Letter on the CDC and FDA, December 4th, 2011
2011 DEC 4 -- DiscoveRx announced the release of the most detailed comprehensive assessment of interaction profiles of known kinase inhibitors across the kinome published to date in the November 2011 issue of Nature Biotechnology, titled "Comprehensive analysis of kinase inhibitor selectivity." This seminal publication utilizing the KINOMEscan platform, wholly-owned by DiscoveRx Corporation, in collaboration with Ambit Biosciences®, quantitatively assessed the interaction patterns of 72 kinase inhibitors against 442 kinases, and included all major kinase groups plus a panel of 54 clinically relevant mutants and several activation state-specific ABL assay pairs. This work...
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