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Vaccines

Research Data from University of Toronto Update Understanding of Vaccines

Published in Medical Letter on the CDC and FDA, January 29th, 2012

2012 JAN 29 -- According to the authors of recent research from Toronto, Canada, "This study examines the role of measured and unmeasured confounding in the relationship between the 2008-9 seasonal influenza vaccine and pandemic H1N1 (pH1N1) influenza virus. Data were taken from a test-negative case-control study of 462 lab confirmed pandemic A/H1N1 (pH1N1) cases and 484 test-negative controls."

"Adjusted odds ratios (OR) and 95% confidence intervals (Cl) were derived using multivariate logistic regression. The analysis was repeated using propensity matching. A sensitivity analysis was conducted to quantify the impact of a hypothetical unmeasured...

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