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HIV/AIDS
Proteologics Granted First siRNA Patent in the Ubiquitin Ligase Field
January 25th, 2008
Proteologics Inc. announced that it has been granted United States Patent No. 7,268,227 relating to its leading antiviral program. This patent broadly covers siRNA molecules that can inhibit, or "silence" the expression of Proteologics' antiviral drug target, hPOSH - a human protein that was characterized by Proteologics as a ubiquitin ligase essential for HIV biogenesis. Proteologics has anti-viral drug discovery programs based on proprietary research of host-protein ubiquitin-ligase drug targets shown to be essential for the HIV life cycle. Proteologics strategy is to target human pathways evolutionarily required for viral biogenesis consequently preventing completion of the viral life...
Source: Medical Patent Business Week (2008-01-25)
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