Medical Patent Law Weekly
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Drug Delivery
Coated nanoparticles solve a sticky drug delivery problem
February 14th, 2007
The layers of mucus that protect sensitive tissue throughout the body may also keep helpful medications away. To overcome this hurdle, Johns Hopkins researchers have found a way to coat nanoparticles with a chemical that helps them slip through this sticky barrier. During experiments with these coated particles, the researchers also discovered that mucus layers have much larger pores than previously thought, providing a doorway that should allow larger and longer-acting doses of medicine to reach the protected tissue. The team's findings were reported in the Early Online Edition of Proceedings of the National Academy of Sciences. ...
Source: Medical Patent Law Weekly (2007-02-14)
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