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Alteon, Inc.

Phase II trial of Alagebrium initiated in erectile dysfunction

Published in Medical Verdicts and Law Weekly, February 17th, 2005

Alteon, Inc., (ALT) announced that it has initiated a phase II trial of its novel A.G.E. Crosslink Breaker compound alagebrium chloride (formerly known as ALT-711) in erectile dysfunction (ED).

EMERALD (Evaluation of Alagebrium in Erectile Dysfunction in Diabetic Males on PDE5 Inhibitors) will assess the ability of alagebrium to restore erectile function in diabetic patients with moderate to severe ED who achieve limited benefit from current treatment with phosphodiesterase type 5 (PDE5) inhibitors, the first class of orally active compounds approved for the treatment of ED.

Alagebrium has demonstrated an ability to reverse ED in a preclinical model...

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