Cambridge Inst. for Medical Research, U.K.

Mechanism of motor neuron disease described

Published in Medical Verdicts and Law Weekly, July 28th, 2005

A new study reports a new mechanism underlying motor neuron disease, which may be broadly relevant to several adult-onset neurodegenerative diseases, including amyotrophic lateral sclerosis, Huntington disease, Parkinson disease and Alzheimer disease.

Mutations in the gene encoding dynein, a molecule involved in transporting cargo in neuronal cells, had previously been shown to cause motor neuron disease.

David Rubinsztein and colleagues at the Cambridge Institute for Medical Research now show that reduced dynein function impairs the clearance of protein aggregates from affected neurons. These aggregates (also called inclusions) are a common feature...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of Medical Verdicts and Law Weekly

Source: Medical Verdicts and Law Weekly (2005-07-28)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry