Published in Medical Verdicts and Law Weekly, December 14th, 2006
Study 1: A molecularly cloned, replication-competent R5 simian-HIV encoding HIV clade C env is mucosally transmissible.
According to recently published research from the United States, "Human immunodeficiency virus type 1 (HIV-1) clade C causes >50% of all HIV infections worldwide, and an estimated 90% of all transmissions occur mucosally with R5 strains.
"A pathogenic R5 simian-human immunodeficiency virus (SHIV) encoding HIV clade C env is highly desirable to evaluate candidate AIDS vaccines in nonhuman primates. To this end, we...
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