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Adverse Drug Reactions

Reports summarize adverse drug reactions research from Johns Hopkins University, Department of Medicine

Published in Medical Verdicts and Law Weekly, January 18th, 2007

Scientists discuss in "Sirolimus monotherapy versus sirolimus in combination with steroids and/or MMF for immunosuppression after liver transplantation" new findings in adverse drug reactions. According to recent research from the United States, "Calcineurin inhibitor (CI)-associated renal dysfunction has emerged as a major cause of morbidity and mortality after liver transplantation. In this retrospective study, we compared the efficacy, safety, and renal protective effect of sirolimus monotherapy (Group A; n=26) with sirolimus in combination (Group B; n=34) with steroids and/or mycophenolate mofetil (MMF) in liver transplant recipients who were switched from CI."

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