Breast Cancer
Research data from University of Heidelberg update understanding of breast cancer
Published in Medical Verdicts and Law Weekly, August 2nd, 2007
"Microarray gene expression profiling has indicated that complex molecular gene expression signatures might be predictive of outcome after systemic treatment for early breast cancer. Neoadjuvant systemic therapy (NST) with its assessment of pathologic complete response (pCR), so far the best surrogate parameter for cure, provides a unique opportunity to rapidly identify such molecular predictors. Currently, an International, randomized phase II study of 2 sequential regimens as NST is being conducted in patients with primary invasive breast cancer T2-4a-c N0-2 MO," scientists in Heidelberg, Germany report.
"Patients receive 4 cycles of doxorubicin/pemetrexed, followed...
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