Hemophilia

Research on hemophilia described by P.S. Owen and colleagues

Published in Medical Verdicts and Law Weekly, July 10th, 2008

According to recent research from the United States, "Recombinant human coagulation factor VIIa (rVIIa) is a procoagulant indicated for treatment of bleeding in patients with hemophilia. A large proportion of rVIIa utilization is for off-label administration in nonhemophiliac patients with acute hemorrhage."

"Concerns of potentially inappropriate use, safety, and cost of rVIIa led to efforts to standardize use of this agent. To comparatively describe the utilization of rVIIa upon implementation of an evidence-based guideline at a university hospital. With advisory direction from a multidisciplinary task force, an evidence-based guideline for use of rVIIa was developed,...

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Source: Medical Verdicts and Law Weekly (2008-07-10)

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