Muscular Dystrophy

Studies from M.L. Sveen and colleagues yield new information about muscular dystrophy

Published in Medical Verdicts and Law Weekly, January 1st, 2009

"Studies in a dystrophinopathy model (the mdx mouse) suggest that exercise training may be deleterious for muscle integrity, but exercise has never been studied in detail in humans with defects of dystrophin. We studied the effect of endurance training on conditioning in patients with the dystrophinopathy, Becker muscular dystrophy (BMD)," scientists in Copenhagen, Denmark report.

"Eleven patients with BMD and seven matched, healthy subjects cycled 50, 30 min sessions at 65 of their maximal oxygen uptake (VO2max) over 12 weeks, and six patients continued cycling for 1 year. VO2max, muscle biopsies, echocardiography, plasma creatine kinase (CK), lower extremity muscle...

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Source: Medical Verdicts and Law Weekly (2009-01-01)

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