Enzyme Research

Research from Nanyang Technological University has provided new data on enzyme research

Published in Medical Verdicts and Law Weekly, October 1st, 2009

"Drug eluting stents (DES) have become a common mode of treatment for stenosis in coronary arteries. However, currently, the use of sirolimus/paclitaxel-coated DES has come under scrutiny, because of their pro-thrombotic effects leading to potential adverse outcomes in the long run," scientists in Singapore, Singapore report.

"We have previously documented that d-threo-1-phenyl-2-decanoylamino-3-morholino propanol (D-PDMP); an inhibitor of glucosylceramide synthase and lactosylceramide (LacCer) synthase markedly inhibited platelet-derived growth factor (PDGF)-induced cell proliferation. We have fabricated DES wherein, D-PDMP or sirolimus was coated on to a double layer...

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Source: Medical Verdicts and Law Weekly (2009-10-01)

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