Published in Medicine and Law Weekly, September 10th, 2004
"Toll receptors in Drosophila contribute to host defense and establish the body plan. Mammalian homologues of Toll, the Toll-like receptors (TLRs), are thought to function only in host defense," explained G.B. Johnson and colleagues.
In a study in mice, Johnson's team found "that mice harboring mutations in TLR4 or in CD14, a co-receptor for TLR4, have an 'ideal' body plan consisting of increased bone mineral content, density, and size as well as decreased body fat."
According to the...
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