Medicine and Law Weekly

OSI Pharmaceuticals - Trials for tumor-blocking pancreatic cancer drug plus chemotherapy promising

Obafemi Awolowo University, Ife - Total lymphocyte count not a substitute for CD4 cell count in HIV management

Obese Elderly - Michigan insurers offer grants for programs to reduce obesity

Obstetrics - Case reported of postpartum sacral fracture presenting as lumbar radiculopathy

Obstetrics - Laparoscopy can be useful for guiding D&C in angular pregnancy

Ohio Tobacco Use Prevention & Control Foundation - Ohio stand teens navigate corn maze to curb tobacco use among peers, others

Ohio Tobacco Use Prevention & Control Foundation - Statewide smoking cessation line helps Ohioans quit

Omnicare, Inc. - Pharma care company provides case management services for retirees

OncoGenex Technologies Inc. - Gene technology company appoints new member to board of directors

Ophthonix Inc. - Vision care company receives fourth patent of 2004

OraSure Technologies, Inc. - Early trial set in patent infringement lawsuit against Schering-Plough

Oragenics, Inc. - Edmund Mickunas named VP regulatory and clinical affairs

Osaka City University - A new bone-graft substitute has osteoinductive and biodegradable properties

Osaka City University - Mutant mice reveal the characteristics of pseudogenes

Otsuka America Pharmaceutical, Inc. - Pharmaceutical company promotes Terry Prime to VP of marketing

Ottawa Regional Cancer Centre - ATF4 is translationally regulated by hypoxic stress

Ovarian Cancer - Gene amplification is one mechanism for hK6 overexpression in ovarian cancer

Oxford BioMedica - Neurobiological gene therapy company signs license agreement for enzymes

PA Consulting Group - Pfizer purchases Meridica Limited from consulting company

PAREXEL International Corporation - Biopharmaceutical outsourcing company introduces PAREXEL consulting

Paladin Labs Inc. - Canadian pharmaceutical company realigns product pipeline

Pathogen Detection - Companies to co-develop automated system to identify airborne pathogens

Penninsula Medical School, Devon - New animal model for studying diabetes described

Pennsylvania State University - Unrecognized iron deficiency can impair immunity in older women

Pennsylvania State University - Variables affect substance P measurement in heart, lung, and skin tissue

Personnel - Adamson to remain as CEO of Medical Staffing Network Holdings

Personnel - Merial announces retirement of executive chairman

Personnel - NDCHealth announces organizational change

PharmaFrontiers Corp. - Company specializing in stem cells announces new CEO

Pharmaceutical Profiles - Clinical development specialist targeting India as potential growth area

Pharmacyclics, Inc. - Pharma company releases data from phase 1 for nonHodgkin's B-cell lymphomas

Philanthropy - Dell supplying computers for U.S. CDC emergency response center

Philanthropy - Vermont couple donate $2.5 million to Fletcher Allen

Phoenix Health Systems' - HIPAA deadline generates interest in technology company's security templates

PhotoCure - Swedish regulatory authorities to approve novel imaging drug Hexvix

Picis - Information technology company automates University of Iowa Hospitals

Pitie-Salpetriere Hospital, Paris - Higher amprenavir plasma minimal concentration associated with lower resistance

Pneumococcal Vaccines Accelerated Development and - Researchers and policy makers asked to "fast track" access to childhood vaccines

Prescription Drugs - Allergan psoriasis treatment tazarotene denied approval by FDA

Prescription Drugs - Health group proposes bills to cut drug costs in Maryland

Prescription Drugs - Program to help poor in New Mexico get medications

Procter & Gamble Health Science Institute - ThermaCare launches heat wrap for knee pain

Procter & Gamble Pharmaceuticals - FDA grants priority review to testosterone transdermal system for HSDD

Prometheus Laboratories Inc. - Specialty pharmaceutical company announces management appointments

ProstaLund Operations - Study shows microwave treatment is as good as open surgery for enlarged prostate

Prous Science, Barcelona - Revaprazan hydrochloride safe and effective for gastric acid inhibition

Rabin Medical Center, Israel - Metformin being evaluated for improving PCOS symptoms

Rambam Medical Center - Dental appliances effective in treating sleep disorder

Ranbaxy Laboratories Limited - Pharma company approved to manufacture loratadine and pseudoephedrine tablets

Rankings - Express Scripts named to the Information Week 500

Regency Hospital Company - Valley Hospital located in Minneapolis acquired by management company

RegeneRx Biopharmaceuticals, Inc. - Pharma company files IND with FDA to initiate trial for chronic pressure ulcers

Rehab. Center of Cardiovascular Diseases, Berlin - Obesity and cardiovascular diseases reviewed

Remon Medical Technologies Ltd. - Medical device company raises $16 million in series C financing

Research Funding - Agriculture secretary announces grants to promote healthier children

Review Med L.P. - Worker's compensation and liability assistance company names president

Rochester Medical Corporation - Medical device company extents marketing and sales agreement for catheters

Roswell Park Cancer Institute - New sequence involved in DNA replication timing may aid in cancer detection

Rovira i Virgili University, Reus - Sultosilate decreased concentration of small, dense, atherogenic LDL particles

San Raffaele Hospital - ESAT-6 and CFP-10 protein peptides used to detect M. tuberculosis

Sciona, Inc. - DSM Venturing invests in company that develops genetic tests

Scripps Research Institute - Genetic signatures profile kidney transplant rejection status

Seattle Genetics, Inc. - SGN-30 phase 2 clinical trial for cutaneous lymphoma initiated

Seoul National University - Synthetic curcumin analogs curtail genes related to angiogenesis

Serono International - Marketing authorization for psoriasis drug granted by European Commission

Siemens Medical Solutions - Heart center, developer collaborate to research uses of MRI in cardiac care

Siemens Medical Solutions - Soarian IT system for healthcare providers installed at medical centers

Sigma-Aldrich Corporation - Nicholson Metabolic Pathways Charts to be developed, published in print, online

Silverlink Communications - Voice communication software system for healthcare enterprises launched

Slovak Academy of Sciences - Grape-derived alkaloids have potent antioxidant activity

Sontra Medical Corporation - Medical devices company picks distributor for rapid skin anesthesia product

Sopherion Therapeutics - Biopharm company raises $47 million, acquires North American rights to Myocet

South East London Strategic Health Authority - Late diagnosis of pulmonary tuberculosis led to community outbreak

Sports-Related Injuries - Motion DNA launches high school sports testing programs

St. Joseph's Parkwood Hospital - Hospital reports increase in number of people with mild, consistent memory loss

St. Jude Children's Research Hospital - Enzyme maintaining chromosome ends is linked to cancer recurrence

St. Louis University - Hepatitis C virus F protein and core protein are dissimilar

St. Louis University - Mechanical strain can alter tissue-factor activity in rat osteosarcoma cells

St. Luke's Roosevelt Hospital - Combined calcipotriene and corticosteroid can repigment vitiligo

St. Marks Hospital - Interleukin-10 gene therapy ameliorates colitis in murine models

Stanford University Medical Center - Researchers encouraged by early study results of drug to treat kleptomania

Sullivan Commission on Diversity in Healthcare - Diversity in U.S. healthcare professions is separate, unequal, commission says

Sungkyunkwan University - The L/L genotype of catechol-O-methyltransferase correlates with panic disorder

Surgical Techniques - Patient dies after surgery telecast live to medical meeting

Sutter Health - Hospitals group launches Spanish-language site for pregnant women, new mothers

Swedish Institute for Infectious Disease Control - Parenteral and mucosal DNA vaccination enhances SHIV infection control

T&F Informa - Business and marketing publication launches

Takeda Pharmaceutical Co., Ltd. - HTG's gene-expression technology to support company's pharmaceutical research

Tampere University - Serum PSA screens have high sensitivity in Finnish population

Technical Univ. of Munich - Gatifloxacin regimens as effective as oral ciprofloxacin for UTI

Technical University of Munich - Active NF-kappa B signaling is prerequisite for influenza infection

Technical University of Munich - Herpesvirus induces IFN-alpha via Toll-like receptor pathways

Technion-Israel Institute of Technology - Saliva plays role in development of oral cancer

Tel Aviv University - Photodynamic agent hypericin has antimetastatic activity in darkness

Telik Inc. - Novel insulin receptor activator prevents PI-induced insulin resistance

Telik, Inc. - Study of application of TRAP drug discovery technology published

Temple University - Evidence builds for potential new cancer drug target

Temple University - JC virus agnoprotein inhibits DNA repair after DNA damage

Teva Pharmaceutical Industries Ltd - U.S. FDA grants tentative approval for generic antihistamine HCL tablets

The Institute For Genomic Research - Scientists decipher genome of ancient pathogen used in biological weapons

The Medicines Company - Company gets E.C. approval to market anticoagulant for PCI patients in Europe

Therapeutic Cloning - Creator of Dolly the sheep applies for license to clone human cells for research

Toronto General Hospital - Novel candidate genes for systemic metastasis identified

Toyama Medical and Pharmaceutical University - Scopadulciol-related molecules are weak mediators of cancer gene therapy

Tracer Analytics - Financial analyses, intelligence company for life science launches LSI 100 Index

Transax International Limited - Medical software company signs 2-year contract with Brazilian insurance group

Tuberculosis - Medical Services invited to participate in tuberculosis study

Tufts University School of Medicine - Renal transplantation results from DCD and DBD donors are equivalent

Type 2 Diabetes - Millions of Asian Americans and Pacific Islanders at increased risk

Tzu Chi University - Microenvironment has a strong bearing on the activity of syndecan-1

U.S. Centers for Disease Control & Prevention -  Mycobacterium tuberculosis transmitted via lung transplantation

U.S. Centers for Disease Control & Prevention - PCR method developed for rapid identification of Nocardia farcinica

U.S. Centers for Disease Control and Prevention - Eradication program has almost wiped out parasitic disease

U.S. Centers for Disease Control and Prevention - Vietnam veterans had higher death rates after discharge than other veterans

U.S. Dept. of Health and Human Services - New DVDs to help combat childhood obesity

U.S. Food & Drug Administration -  Salmonella and E. coli may grow in oranges meant for juice

U.S. National Cancer Institute - SV40 pseudovirions are efficient gene vectors

U.S. National Institutes of Health - Adiponectin levels affected by renal function and diabetes duration

U.S. National Institutes of Health - Efficient magnetic cell labeling for cellular MRI accomplished

U.S. National Institutes of Health - Group A Streptococcus strains causing epidemics analyzed

U.S. National Institutes of Health - Hydroxyapatite particles stimulate human monocytes IL-18 production in vitro

U.S. National Institutes of Health - Novel potentially defective CYP2C9 alleles identified

U.S. National Institutes of Health - Reactions with haptoglobin-hemoglobin complex modulate NO reaction products

U.S. National Institutes of Health - Simian virus-tainted polio vaccine does not raise childhood cancer risk

U.S. Population Council, New York - N-9-containing lubricants may enhance rectal transmission of HIV and other STDs

Umea University - Study demonstrates the expression of BNP the rat heart during growth

Univ. Wisconsin Hospital & Clinic - Combination antimicrobials do not reduce mortality in Gram-negative bacteremia

Univ. of Medicine & Dentistry, New Jersey - Researchers describe negative receptors of cardiac hypertrophy

Univ. of Texas Medical Branch, Galveston - Mexican American communities offer health benefits to long-time residents

Univ. of Texas SW Medical Center - VEGF₁₆₅ antagonizes semaphorin 3B-initiated apoptosis in cancer cells

Univ. of Texas, Austin - Chemical derived from vitamin E shows early promise as cancer drug

University College London - APOA4 T347S variant linked to reduced plasma TAOS in diabetic patients

University Hospital Cleveland - Increased drug resistance reported in Streptococcus pneumoniae isolates

University Hospital Gasthuisberg - Acne-like rash linked to effectiveness of new targeted cancer treatment

University Hospital Maastricht - Inflammatory mediators normalize with weight loss in morbidly obese patients

University Hospital, Lund - Immunohistochemical markers of poor prognosis identified

University Hospital, Munster - Xenon improves recovery from myocardial stunning in dogs

University of Aalborg - Temporal characteristics of descending inhibitory control vary by gender

University of Alabama - Whole genome amplification secures enough DNA for typing HLA variants

University of Arkansas of Medical Sciences - PPAR-gamma agonist reduces S. aureus-induced microglial activation

University of Auckland - Randomized trial of an alternative to heparin in cardiac surgery is encouraging

University of Barcelona - Few patients have good virological response after 2 years treatment interruption

University of Bath - Surface plasmon resonance can detect P. aeruginosa on gold

University of Bologna - HA-coated screws decrease fixation failure incidence of trochanteric fractures

University of Bologna - Novel Akt inhibitors reduce drug resistance in leukemic cells

University of Bordeaux I - Platelet factor 4 uses several avenues for angiogenesis suppression

University of Bristol - Type 1 diabetes risk defined by leukocyte antigen class II genotype

University of California San Diego - TTF-1 expression is specific for lung primary in typical and atypical carcinoids

University of California San Francisco - Structural differences identified in transmembrane of mouse, human NKG2D

University of California, San Diego - Packaging HIV vectors with FIV is viable alternative to HIV structural proteins

University of California, San Francisco - Researchers verify a functionally graded interphase between cementum and dentin

University of Cambridge - Vaccine elicits anti-angiotensin I antibodies in hypertensive subjects

University of Colorado - Term placentas from high-altitude pregnancies don't suffer hypoxic stress

University of Dundee - Research on trypanothione could lead to drug for three tropical diseases.

University of Dusseldorf - New cord blood somatic SCs has intrinsic pluripotent differentiation potential

University of Edinburgh - Role of Plasmodium falciparum genes in malaria in pregnancy reviewed

University of Erlangen - Function of S. cerevisiae Yaf9p protein clarified

University of Essex - Immunoporation provides stable cell line transfection

University of Florida - Consider gender and racial differences in BP response in dobutamine testing

University of Freiburg - Utility in four-fragment proximal humerus fractures determined

University of Gottingen - Macrophages generate cytokines that stimulate breast cancer invasion

University of Graz - Thyrotropin-releasing hormone reduces leptin levels in children and adolescents

University of Heidelberg - Carotid artery stenting has not proven its safety or efficacy

University of Hong Kong - HLP gene expression in C. glabrata may play a role in hemolysin production

University of Hong Kong - VEGF and its receptor mediate macrophage action in small-for-size liver grafts

University of Illinois - Stenting reduces restenosis in small coronary arteries as well as larger ones

University of Illinois - Survey shows women unaware of infertility risk factors

University of Illinois - Wealth does not create happiness and it doesn't build a strong country, either

University of Illinois at Chicago - Powerful MRI machine for decoding human brain unveiled at Illinois University

University of Iowa - Flavin-dependent thymidylate synthase activity characterized

University of Iowa - The terms "plastic surgery" and "cosmetic surgery" are perceived differently

University of Kansas - New guideline evaluates treatments for post-herpetic neuralgia

University of Leicester - Cellular endothelial compartment increase may play pathologic role

University of Leipzig - GB virus C viremia associated with increased quality of life in HIV infection

University of Lleida - Data highlight a mechanism for survival advantage in cardiac fibroblasts

University of Louisville - Physiological coxa varus-genu valgus may affect knee and ankle joint moments

University of Lund Hospital - Cyclin D2 grants myeloid progenitors the ability to minimize cytopenia

University of Maryland - Production of bioproducts via transgenic animal models may soon be a reality

University of Michigan - Antitumor responses promoted by bone marrow from immunized donors

University of Michigan - Injectable microparticle-gel system provides prolonged local lidocaine release

University of Milan - Optimal coating agents determined for oral drug delivery system

University of Minneapolis - Gene-specific PCR provides rapid detection of E. coli clonal group

University of Minnesota - Children's exposure to air pollutants most influenced by air in the home

University of Mississippi - Angiotensinogen mRNA-stabilizing protein blockade lowers rodent blood pressure

University of Munich - Conditioned postural reflex is difficult for cerebellar patients

University of Munich - Homozygous myotonic dystrophy type 2 mutations produce more subtle phenotypes

University of Munich - Polymorphisms in the serotonin 2C receptor are not linked to suicide risk

University of Nebraska - Folate regulates the way Hox genes influence the skeletal phenotype

University of Nijmegen - Transforming growth factor-beta 3 may not promote wound healing

University of North Carolina - Cleavage of HIV-1 GagPol precursor by activated protease occurs intramolecularly

University of North Carolina - Possible mechanism of arsenic-induced diabetes proposed

University of North Carolina - Single-LTR HIV-1 vector is optimized for functional genomics applications

University of Orebro - Effects of training and detraining on muscle satellite cells determined

University of Otago, Dunedin - Parallel guiding planes increase stability of removable partial dentures

University of Pennsylvania - A novel rodent neck pain model is developed to evaluate persistent pain

University of Pennsylvania - High level of hope positively related to coping in cancer patients

University of Pennsylvania - No difference in results between enzyme inhibitors and receptor blockers

University of Pittsburgh - Cigarette smoke causes breaks in DNA and defects to a cell's chromosomes

University of Pittsburgh - CpG DNA-mediated immune response may counteract pulmonary gene therapy

University of Pittsburgh - Study investigated trends in atrial fibrillation admissions to U.S. hospitals

University of Rochester - Depression also a problem in patients with Parkinson disease

University of Rome La Sapienza - Low-frequency power may aid in stratifying the risk of sudden death

University of Santiago de Compostel - Effect of particle size on transport across nasal mucosa studied

University of Sao Paulo - Genetic markers of breast tumor estrogen/progesterone receptors identified

University of Southern California - T- and B-cell lymphoma demographics/immunology in HIV-infection characterized

University of St. Etienne - Nosocomial transmission of hepatitis C virus plagues Tunisian dialysis patients

University of Tampere - CCND1 overexpression common in male patients

University of Tartu - Tissue plasminogen activator expression characterized in human CNS

University of Tennessee - Preoperative upper endoscopy for laparoscopic gastric bypass is necessary

University of Texas - Neuropeptide Y antagonism lowers reflex cutaneous vasoconstriction

University of Texas - Strategies are proposed to increase use of percutaneous coronary intervention

University of Turku - Marathon running does not cause marked change in cardiac function in healthy men

University of Vienna - Closed tracheal suctioning system lowers gastric-bronchial cross-contamination

University of Virginia - Phosphorylation of Y845 mediates binding to the mitochondrial protein

University of Virginia - Walking associated with reduced risk of dementia in older men

University of Wales - Calcium intake and vigorous daily exercise necessary to build bone density

University of Wales College of Medicine - Number of positive sentinel nodes may predict nonsentinel node metastasis

University of Washington - A glass of cranberry juice a day may keep bladder infection away

University of Washington - Far more men than women favor routine paternity testing at birth

University of Wisconsin - Cytochrome P450 play a role in drug metabolism

University of Wyoming - Review summarizes the role of acetaldehyde in alcoholic cardiomyopathy

Urologe A - Diagnosis and treatment of relatively rare gynecologic cancer discussed

VECTORsgi - Companies form alliance to automate HIPAA transaction processing

VHA Inc. - $1 million awarded by foundation for healthcare innovations

VISTA Staffing Solutions - New VISTA staffing unit offers temporary oncologist staffing

Valley Hospital, Ridgewood - New Jersey hospital to offer newly approved stent device to prevent stroke

Vanderbilt University - Low T-cell receptor diversity associates with CTL escape in chronic hepatitis C

Vanguard Health Systems - Blackstone Group completes major investment in acute care hospitals company

Verispan - Company receives U. S. patent for de-identified patient encryption process

Veterans General Hospital, Taipei - Amyloid precursor protein is a prognostic marker for oral carcinogenesis

Vical Incorporated - Biopharmaceutical company announces European patent developments

Vicuron Pharmaceuticals Inc. - Dunton and Wenzinger appointed to biopharmaceutical company's board of directors

VisiJet Inc. - U.S. FDA approves device for separating corneal tissue during surgery

Vital Images - Medical imaging software company shops U.S. FDA-cleared diagnostic software

Vivant Medical - Clinical study of microwave ablation for lung cancer to begin at RI hospital

Washington Hospital Center - Contrast agent does not compromise therapeutic bone marrow-derived cells

Washington University - AD disease is not accelerated aging

Washington University - Molecular motor implicated in tissue remodeling

Washington University - New system would vastly improve heart defibrillation

Washington University - Researchers identify "light meter" that controls pupil constriction

Wayne State University - Study explores marital partners' perspectives of health-related exchanges

Wellington Hospital - Nonanatomical Dexter model suitable for endoscopic dexterity training

West Nile Virus - Second Illinoisan dies of West Nile virus

West Nile Virus - Two new cases of West Nile reported

Western Michigan University - Effects of HPV-18 proteins on keratinocyte gene expression determined

Wilford Hall USAF Medical Center - At-home diagnostic test for sleep disorder developed

Wockhardt Biotech - President of India inaugurates new biotech park

Wyeth Research - Inexpensive thermal shift assay developed

Wyeth Vaccines Research - Recombinant respiratory syncytial viruses characterized

YORKTEST Laboratories - Trial appears to validate finger-stick food-intolerance test

Yamanouchi Pharmaceutical Company, Ltd. - Endothelin ET_A receptor antagonist reverses pulmonary hypertension

dj Orthopedics, Inc. - Orthopedics company names member to board, releases back bracing system

eResearchTechnology, Inc. - Pharmaceutical company signs $1.9 million software and services agreement

pSivida Limited - Australian nanotechnology firm spins out diagnostics company

sanofi-aventis Group - Eloxatin to receive expanded indication in Europe for early-stage colon cancer