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University of Dusseldorf

New cord blood somatic SCs has intrinsic pluripotent differentiation potential

Published in Medicine and Law Weekly, October 22nd, 2004

New somatic stem cells from cord blood have intrinsic pluripotent differentiation potential.

"Here a new, intrinsically pluripotent, CD45-negative population from human cord blood, termed unrestricted somatic stern cells (USSCs) is described. This rare population grows adherently and can be expanded to 1015 cells without losing pluripotency.

"In vitro USSCs showed homogeneous differentiation into osteoblasts, chondroblasts, adipocytes, and hematopoietic and neural cells including astrocytes and neurons that express neurofilament, sodium channel protein, and various neurotransmitter phenotypes," researchers in Germany report.

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