National University of Singapore
Glutamate receptor expression in retina diabetic rats examined
Published in Medicine and Law Weekly, October 22nd, 2004
"This study was aimed to investigate the expression of glutamate receptors and calcium-binding proteins in 1- and 4-month streptozotocin (STZ)-induced diabetic rats. Upregulation of glutamate receptors' [N-methyl-D-aspartate receptor (NMDAR)l and GluR2/3] immunoreactivities was observed in the ganglion, amacrine and bipolar cells as well as in the inner and outer plexiform layers (IPL and OPL) in 1-month diabetes and was further enhanced at 4 months. Immumoreactivity of calcium-binding proteins (calbindin and parvalbumin) was...
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