Medicine and Law Weekly

Merck &. Co., Inc. - Merck withdraws Vioxx based on 3-year data from APPROVe clinical trial

Merck Research Laboratories - Novel HIV-1 integrase inhibitor has potent antiviral activity

Metabolic Explorer - Biotechnology company announces appointment of new chief financial officer

Michigan Public Health Institute - Research center wins federal contract to evaluate rural health program

Microbix Biosystems Inc. - Proprietary influenza virus yield enhancement technology to be relicensed

Minnetronix, Inc. - Medical device product development company named as Tekne Award finalist

Misonix, Inc. - Ultrasonic, air pollution systems manufacturer announces promotions

Mount Sinai School of Medicine - AGE receptor 1 negatively regulates inflammatory response

Nabi Biopharmaceuticals - Positive results announced from NicVAX trial for smoking cessation

Nagano Matsushiro General Hospital - Long-term outcome of cementless, cruciate-retaining prosthesis determined

National Heart and Lung Institute - Cutting household allergen levels unlikely to have much impact on asthma

National Inst. for Public Health, Bilthoven - Ethanol and bleach insufficiently inactivate norovirus model

National Inst. of Standards & Technology - World Trade towers design exceeded wind load codes

National Institute for Medical Research, London - Antibodies to Plasmodium MSP1₁₉ form ring structures with antigen

National Research Council of Canada - Novel process improves data mining of gene expression changes

National Research Council, Italy - Common mechanisms facilitate the death of neurons

National Science Foundation - Midwest thunderstorm study points toward better forecasts

National Tropical Botanical Garden, Hawaii - Mechanism proposed for development of neurodegenerative disease in Guam

National University of Ireland, Cork - Rapid real-time PCR detects/quantitates M. avium subspecies in contaminated milk

National University, San Luis - Variable cholinergic agent activity in estrous cycle regulates ovarian steroids

Natus Medical Incorporated - Newborn health screening company acquires Fischer-Zoth

NaviCath Ltd. - Remote-control PCIs may aid cardiologists

NeoPharm, Inc. - Drug company director files definitive consent statement to restructure board

Nestec Ltd - Matrix-bound nitrofuran residues in honey analyzed

New York-Presbyterian Hospital - Intracoronary radiation shows no benefit in 5-year study

NexMed, Inc. - Transdermal treatment company files IND for nail fungal infection treatment

Niigata University - High-dose cytosine arabinoside/etoposide + TBI feasible in HSCT for ALL

North Shore-Long Island Jewish Research Institute -  DYT1 mutation linked to microstructural white matter changes

Northwestern University - Allogeneic HSCT induces remission of severe and refractory rheumatoid arthritis

Northwestern University - Psychological adjustment to twins after infertility needs more study

Novartis AG - Higher dose of Gleevec improves progression-free survival in GIST study patients

Novartis Pharma - Long-term zoledronic acid therapy prevents loss of bone, strength in OVX rats

Novo Nordisk - Pharma company granted rights to AERx insulin diabetes management system

Novo Nordisk AS - Engineering predictability and protraction in a basal insulin analogue

Nucletron B.V. - Device company announces image-guided treatment, reconstruction software

Nuvelo, Inc. - Drug discovery company reports acute peripheral arterial occlusion trial

ONCURA - Medical device company introduces IceRod, minimally invasive cryoneedle

OXiGENE, Inc. - Data released on preclinical compound confirming its antitumor activity

Obafemi Awolowo University - Diabetes-specific quality of life scale validated in Nigerian hospital

Odense University - Attenuation correction caused a diagnosis change in 1/5 of abnormal studies

Okayama University - Bone metabolism differs between teen and adult female long-distance runners

Oncolytics Biotech Inc. - Biotechnology company presents data on anticancer effects of cytotoxic agents

Orebro University Hospital - Hospital-acquired C. difficile infection 1300-fold higher than in community

Oregon Health & Science University - Dantrolene and chlorzoxazone linked to rare serious hepatotoxicity

Oscient Pharmaceuticals Corporation - Pharmaceutical company accelerates FACTIVE sales force expansion

Ospedale Maggiore, Milan - African Burkitt lymphoma treated with CEOP polychemotherapy

PROKARIA - Genomics develops novel strand-displacing DNA-Polymerase

Paratek Pharmaceuticals, Inc. - Pharmaceutical company announces new board member

Pasteur Institute - Genome sequencing to provide insight into pneumonia outbreaks

Patient Confidentiality - HIPAA restricts release of information on injured soldiers

Patient Education - Study recommends education level be added to CHD treatment guidelines

Payless ShoeSource, Inc. - Shoe stores raising money for breast cancer awareness

Peking University - Leptin induces STAT3 and ERK1/2 activation in breast carcinoma cells

Peninsular Medical School - Information-seeking behaviors of prostate cancer patients' partners studied

Pennsylvania Department of Health - Health department awarded grant to impact obesity, diabetes and asthma

Pennsylvania State University - Antisense oligonucleotides targeted to HPV11 E6/E7 RNA stop papilloma growth

Perlegen Sciences, Inc. - Genomics company awarded grant by the National Human Genome Research Institute

Personnel - Health Language, Inc., appoints new chief technology officer

Personnel - HealthTrans names senior vice president of national sales

Personnel - Healthlink appoints vice president and chief medical officer

Personnel - LocumTenens.com announces Recruit Rx for physician recruitment

Personnel - Magellan Health Services chief medical officer appointed to DMAA board

Pfizer Inc - Pharma company issues statement on withdraw of Vioxx

Pharmaceutical Research Plus, Inc. - Pharma research company and U.S. Wellness unite to deliver patient recruitment

Phase Forward - Data management solution provider partners with research institute

Phase III Medical, Inc. - Healthcare company receives investment from chief operating officer

Philips Medical Systems - Electronics company showcases new cardiovascular imaging technologies

Pomeranian Medical University, Szczecin - Correlations between magnesium status of neonates and mothers from blood/hair

Possis Medical, Inc. - AiMI investigators present full clinical trial results

Presido Sanitario San Camillo - Primary hyperparathyroidism in elderly patients increases hip fracture risk

Primedex Health Systems, Inc. - Diagnostic imaging facilities operator announces capitation contracts

Pro-Pharmaceuticals, Inc. - Pharma company appoints advisory board, retains Hanify & King

Prometic Life Sciences Inc. - Biopharmaceutical company modifies organizational structure

Proxima Therapeutics, Inc. - First 3-year data presented on MammoSite radiation therapy

Purdue Pharma - FDA approves Palladone Capsules (CII) for the management of persistent pain

Purdue University - Sex-related differences in oral ciprofloxacin disposition not only weight-based

QuadraMed Corporation - Physicians' hospital selects healthcare information system

Queen's University - Belfast - Role of suppressor of cytokine signaling in inflammation reviewed

Questcor Pharmaceuticals, Inc. - Pharma company representative discusses vitamin B-12 absorption

RESOLVE - Survey shows women unaware of factors that cause future fertility problem

Regional Medical Res. Ctr., Andaman Nicobar - Dominant leptospire genotype associated with outbreak clusters in India

Reproductive Health - Report shows Philippine population to double in 29 years

Research and Markets - Chemical genomics report now available through online source

Rockefeller University - Dying cells encourage neighbors to grow

Roskilde University Center - Cadmium inhibits DNA mismatch repair

Roswell Park Cancer Institute - Optimal sampling strategy for tissue microarrays determined

Royal Pharmaceutical Society - Got athlete's foot? Reach for the cattle feed

SCHWARZ PHARMA, INC. - Pharma company announces orally dissolving tablets for Parkinson Disease

SUNY Stony Brook - Viruses bearing transgene generate coagulation factor in hemophilia A models

Saarland University - Radiation before chemo and surgery as effective as after

Sahlgrenska University Hospital - PARP-1 gene knock-out protects male mice from perinatal brain injury

Saitama Medical School - Liver enzymes monitor post-surgical liver function in those with HCV antibody

Schering AG - New MRI liver contrast agent Primovist approved in E.U.

Schering Plough Research Institute - Enzyme inhibitors may treat parathyroid hormone-related protein-positive tumors

Scientific Software, Inc. - Software provider to sciences announces new system control of Varian 3900 GC

Scripps Research Institute - Pathogenic molecular clone of FIV clade C characterized

Seattle Genetics, Inc. - Genetics company signs antibody-drug development agreement with Bayer

Seoul National University -  H. pylori RpoB polymorphism correlates with differential induction of IL-8

Seoul National University - Insulin reverses severe cardiovascular toxicity in dogs

Shanghai Academy of Agricultural Sciences - A new PCR-based two-step DNA synthesis method assembles long complex genes

Shape Up America - Koop backs nonprofit to make childhood obesity prevention public health priority

Siemens Medical Solutions - San Jose Light the Night Walk sponsored by radiation therapy equipment maker

Singapore General Hospital - Emergency plans needed in event of bioterrorism or natural epidemic

Song - Delta low-fare air service shakes up pink martini to raise breast cancer funds

Southampton General Hospital - Effects of malathion on cutaneous vasculature elucidated

St. Joseph Hospital, Maine - IGF-1 regulatory system is potential target for bone loss therapy

St. Joseph's Hospital, St. Paul - Minnesota hospital launches program for early identification of dementia

Standard Insurance Company - Insurance company offers online retirement plan loan and distribution service

Stanford University - Catheter-delivered clip facilitates edge-to-edge repair

Stanford University - New atherosclerosis therapies improve the function of the NO synthase pathway

Stanford University - Scientists help bring study of smallpox virus into "molecular age"

Starpharma - Australian company to lead NIH-funded project to prevent HIV, other STDs

State University of Campinas - Tandem repeats of GPIba gene may help to identify risk for MI

State University of Sao Paulo - Acetoacetate inhibits hypochlorous acid

Stiefel Laboratories - James Hartman appointed VP, U.S. marketing by dermatology-focused pharmaceutical

Swedish Medical Center, Seattle - Lower-income patients less informed about cancer treatments

Swiss Federal Institute of Technology - Deafferentation fails to block anorectic effect of hydroxycitrate

Synbiotics Corporation - Veterinary products corporation restructures debt

Synthes, Inc - Swiss medical device company resolves merger control proceedings in Germany

TechniScan Inc. - National Cancer Institute awards imaging company grant

Technical University of Munich - Alternate growth factors foster the neovascularization of Barrett carcinoma

Tel Aviv University -  Lactobacillus GG bacteria ameliorate arthritis in Lewis rats

Texas A&M University - Pain, emotional distress should be treated concomitantly in pediatric cancer

Texas A&M University - Phosphorylation contributes to rates of force development and relaxation

The Aristotle Corporation - Education, medical supplier acquires science products firm Ginsberg Scientific

The North American Menopause Society - Position statement updated on hormone use in menopausal women

Tohoku University - Technique captures flow dynamics produced solely by ventricular expansion

Toronto Hospital for Sick Children - Metalloproteinase modulates fibromatosis size and cell invasiveness

Toronto Western Hospital - Clinical trial failure detailed

Toronto Western Hospital - Early MRI, surgery may enhance spinal trauma recovery

Trakya University Hospital - Pressure-induced tibial pain could be clinical indicator of low bone density

Trans Genic Inc. - Gene-focused company ranked 24th on Deloitte's Fast 50 List in Japan

True Health, Inc. - U.K. service, medical equipment provider to hospitals expands sales area

U.S. Armed Forces Institute of Pathology - Extracellular matrix changes in stented coronary arteries characterized

U.S. Army - Research team develops nonhuman primate model of smallpox infection

U.S. Army Med. Research Inst. of Infec. Disease - Real-time assay to detect monkeypox virus in rodents developed

U.S. Army Med. Research Inst. of Infec. Diseases - Management of laboratory exposures to bioterrorism agents reported

U.S. Genomics - Expansion of genomics company into larger facility follows security contract

U.S. National Institutes of Health - Blocked rhinal cortex D2 receptor protein interrupts learning cues in monkeys

U.S. National Institutes of Health - Hepatocyte growth factor promotes the metastasis of c-Met positive carcinomas

U.S. National Institutes of Health - International effort makes data freely available to scientists worldwide

U.S. Postal Service - Social awareness stamp for sickle cell disease introduced

Univ. Hospital of Epileptology, Bonn - Study shows memory loss after brain surgery

Univ. Mediterranee, Marseille - HIV-1 and MLV Gag sufficient to recruit APOBEC3G into virus-like particles

Univ. of California, Los Angeles - Knowledge of gammaherpesvirus cis elements can be exploited for vector design

Univ. of Texas, Galveston - Air traffic controllers' stress affects later hypertension

Univ. of Wisconsin, Madison - Researchers comment on the severity of "Spanish flu"

University Autonoma, Puebla - Storage temperature affects ability of Streptococcus pyogenes to grow in food

University Buffalo - Prednisolone, other immunosuppressants studied in treatment of lupus

University College London - Algorithm determines origin of dual-site gynecologic tumors

University Florence - Androgen receptor associates with epidermal growth factor receptor

University Giessen - Blood platelet components are important elements of angiogenesis

University Hospital, Geneva - TLR4 involved in endotoxemia-related pulmonary injury

University Medical Center, Rotterdam - Therapeutic action of sumatriptan is mainly due to cranial vasoconstriction

University of Aberdeen - CYP1B1 may be therapeutic target in RCC

University of Adelaide - Fatty acid effects on appetite varies with chain length

University of Alabama - Infectious nontransmissible respiratory syncytial virus developed

University of Alabama, Birmingham - K_ATP cardioprotection does not require moderation of Na⁺ accumulation

University of Alberta - Muscle oxygenation trends during exercise measured by IR spectroscopy

University of Alberta - NIH funds centers to study islet transplantation

University of Athens - Furosemide formulations suitable for transdermal delivery

University of Birmingham - DHEA not recommended for healthy elderly people

University of British Columbia - Release characteristics of paclitaxel-loaded microspheres determined

University of California San Francisco - Immune activation set point is established early in HIV infection

University of California, Irvine - Nobel Prize for chemistry awarded to three scientists

University of California, San Francisco - Gene expression profiles analyzed during CD4+ T cell differentiation

University of Cambridge - LacZ-based transgenic mouse will advance the study of gene repair strategies

University of Chicago - Adenovirus-mediated gene delivery characterizes bone morphogenetic protein

University of Cincinnati - Diazoxide activates Akt through the PI3 kinase signaling pathway

University of Connecticut - Induction through privileged site needs sympathetic nervous system

University of Dundee - Effect of vehicle resistance on transdermal iontophoretic delivery determined

University of Eastern Piedmont - Antioxidants in enteral feeding benefits critically ill patients

University of Florida - Background noise jumbles brain circuits

University of Florida - Women misinterpret health benefits, hazards of hormone therapy

University of Freiburg - Adjustable dendrimers deliver transfection with little or no toxicity

University of Georgia - Ciliary neurotrophic factor induces adipose tissue apoptosis in rats

University of Greifswald - Analyses narrow region on chromosome 4 bearing metabolic syndrome genes

University of Hong Kong - Definition and diagnosis of GERD reviewed

University of Hong Kong - Interactive multimedia aid for prenatal screening evaluated

University of Idaho - Culture-independent methods provide insights into infective bacterial species

University of Iowa - Early predictors of residual hip dysplasia identified

University of Kentucky - Neurological complications of bariatric surgery outlined

University of Kiel - Expression of alphaVbeta₆ characterized in various carcinomas

University of Kuopio - -352G allele frequency higher for early-onset AD in eastern Finnish population

University of Leicester - Study investigates the protective effects of the PKC activator PMA

University of London - Half of Internet Viagra could be counterfeit, new research shows

University of Madras -  Eugenia jambolana seed kernel protects tissue antioxidants

University of Maine - Decline in cognitive function affects adults young and old

University of Manchester - Stem-cell transplants may be used to repair peripheral nervous system

University of Maryland - Genes linked to SLE disease activity identified

University of Melbourne - Ventilating babies with air, rather than pure oxygen, could reduce mortality

University of Minnesota - APOBEC3F properties/hypermutation preferences indicate activity against HIV-1

University of Minnesota - Plasma phytoestrogens unaltered by postmenopausal women's probiotic consumption

University of Munster - Donor CD8+ T cell-mediated TAA-specific antitumor response driven by GVHD

University of Navarra - Antifungal agent protects against adiposity induced by cafeteria diet

University of Ottawa - Increases in CSF[Na⁺] preceded increases in blood pressure and heart rate

University of Oxford - Cardiac factors differ by gender in aging type 2 diabetic rat heart

University of Oxford - Singe polymorphisms in nNOS impair heart rate regulation during exercise

University of Pennsylvania - Foxa2 regulates multiple pathways of insulin secretion

University of Pisa - Haplotype analysis of BRCA1 gene reveals new gene rearrangement

University of Pittsburgh - Artificial trimeric TRAIL has the potential to treat cancer

University of Sao Paulo - Incorporation of multiple membrane proteins into liposomes studies

University of Siena - Marker of oxidative stress elevated in neonates, lower in term infants

University of Southern California - Bladder cancer bank will be effective tool in marker development

University of Surrey - Insulin detemir improves predictability of glycemic control

University of Texas - Novel immunotoxin shows promise in murine model

University of Texas - ap65 gene silencing reduces vaginal epithelial cells adherence by T. vaginalis

University of Texas Medical Branch - RNA viruses alter vector host range, resulting in potential disease emergence

University of Toronto - Quantification of leukocyte recruitment to atherosclerotic lesions is lacking

University of Turin - Hospital emergency admissions are linked to exposure to urban pollutants

University of Utah - Biologists discover gene that helps roots limit leaf growth

University of Utrecht - Postoperative health status measures compared

University of Utrecht - Virosome and ISCOM vaccines protect against Newcastle disease

University of Valencia - Immunogenic antigens of eel pathogen Vibrio vulnificus identified

University of Virginia - $5 million grant targets leukemia drug development, creates new jobs

University of Washington - Pegylated interferon may cause vision disorders in chronic hepatitis C patients

University of Wisconsin - Reduced adiposity by desaturase deficiency is PPAR-independent

University of Zurich - Concurrent infections with vector-borne pathogens caused fatal hemolytic anemia

University of the Basque Country - Enkephalin-degrading enzymes in human semen reviewed

Uppsala University - Pulses of external ATP aid synchronization of pancreatic beta cells

Varian Medical Systems - Image-guided radiation device installed at radiotherapy clinic in Switzerland

Varian Medical Systems, Inc. - Chris Hanna appointed vice president of newly formed oncology information unit

Vasomedical, Inc. - Thomas Glover named president, CEO of cardiovascular-focused company

Veterans Healthcare - U.S. Senate candidate proposes expanded veteran benefits

Vical Incorporated - Phase 1 clinical trial for cytomegalovirus gene encoded vaccine initiated

Virginia Commonwealth University - Fluoroquinolone use predicts rates of resistant Pseudomonas aeruginosa

Visiomed Group Ltd - Application filed with U.S. FDA for childhood asthma incentive spacer

Wake Forest Univ. Medical Center - Soy could be good for the heart and bones of premenopausal women

Wales Heart Research Institute - Atrial natriuretic peptide modifies large artery distensibility

Washington Group International, Inc. - Pfizer awards architectural, engineering services contract for Michigan projects

Wassen International - Selenium-enriched yeast is available and safe, research review shows

Weill Cornell Medical Center - Percutaneous coronary interventions are now more successful

Weis Center for Research - The gamma subtypes of G protein appear similar but perform unique functions

Weizmann Institute of Science - Animal model for PCOS developed

WellPoint Health Networks Inc. - Health insurer joins fight to end teen substance abuse, sponsors CASA family day

West Nile Virus - West Nile cases continue to increase in Nevada

West Virginia University - Cell models developed for chemoresistance studies of human ovarian carcinoma

Wildlife Trust - Hurricanes and extreme weather causing plant diseases

Windrose Medical Properties Trust - Medical properties trust prices equity offering

XXI Century Natl. Medical Center, Mexico City - Genomic testing identifies chromosomal changes in sporadic breast cancer

Xiang Ya Hospital - Body surface area and BMD tie closer than BMD/height or weight in Chinese women

Yale University - Differences between hospitals may account for racial treatment differences

Yale University - Morphology of uterine papillary serous carcinoma precursor described

Yale University - Nonpathogenic, live, viral vaccine vectors responses characterized

Yamanouchi Pharmaceutical Co. - FibroGen to license erythropoietic small molecule in development for anemia

Yokohama Red Cross Hospital - Transvenous catheter cryoablation effective for canine AV junction ablation

Yonsei University, Seoul - Myotubularin-related protein suppresses growth of lung carcinoma cells

Zizhu Pharmaceutical Co., Ltd. - The Female Health Co. forms relationship in China