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Medicine and Law Weekly

Susan Hasty, Publisher

Table of Contents . . . November 26th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Medicine and Law Weekly | Other Publications

Aastrom Biosciences, Inc. - Diabetic limb ischemia clinical trial agreement signed

Abortion - Abortion clinic says it will not require parental consent

Abortion - Challenge to Oklahoma's parental notification law thrown out

Cellerant Therapeutics, Inc. - European patent office grants broad claims on the human hematopoietic stem cell

Centers for Medicare & Medicaid Services - Payment rates and policy changes announced for hospital outpatient services

Coalition for Affordable and Reliable Healthcare - New report lauded as evidence that medical malpractice reform works

Competitive Technologies - After settlement, company licenses homocysteine assay to Bayer

Correctional Medicine - New Alabama healthcare chief says system needs funds, not Band-Aids

Decision Resources - Study shows 16% increase in 2003-2004 HMO Medicare enrollment in 6 states

Endius, Inc. - MIS company acquires intellectual property portfolio from MIS surgery pioneer

Environmental Health - West Virginia residents file lawsuit over chemical leak

Facing Our Risk of Cancer Empowered - Genetic counselors and advocacy group develop genetic discrimination brochure

Finance - Gentiva reports Q3 2004 EPS of $0.17 and double-digit medicare revenue increase

Finance - Information Holdings reports third quarter financial results

Genmab - Antibodies with activity against non-Hodgkin lymphomas characterized

3DM, Inc. - PuraMatrix maker secures $1.7M financing

3M Pharmaceuticals - Bacteria more likely to develop resistance to clindamycin than metronidazole

AEterna Zentaris, Inc. - Deal signed with Tulane for potential anticancer agents

AMS Health Sciences, Inc. - Nutritional supplements company reports loss of $0.15 per share

Academy of Military Medical Sciences, Beijing - Genome content of live plague vaccines defined using DNA microarray

Acadia Pharmaceuticals, Inc. - Pharmaceutical firm earns milestone on advancement of pain drug

Acusphere, Inc. - Pharmaceutical firm reports second closing of $21.5M private financing

Advanced Neuromodulation Systems, Inc. - Device firm reports 37% increase in sales

Aerogen, Inc. - Nebulizer developer reports loss of $0.96 per share

Affymetrix, Inc. - ENCODE array launched to uncover function of human genome

Alaris Medical Systems, Inc. - Alaris Medical Systems extends contract with MedAssets

AlbaNova University Center - Microarray-based AMASE offers a novel way to scan for gene mutations

All-India Institute of Medical Sciences - Frequency-doubled Nd:YAG laser useful for treatment of overhanging blebs

Alnylam Pharmaceuticals, Inc. - Study shows reduction of alpha-synuclein expression by RNA interference

Alpharma, Inc. - FDA approval granted for citalopram hydrobromide tablets

American Diabetes Association - Study: Diabetes drug reduces artery reclogging

American Legacy Foundation - Funding granted to study doctors' smoking cessation practices

American Pharmaceutical Partners, Inc. - Approval granted for amiodarone hydrochloride

American Pharmaceutical Partners, Inc. - Pharmaceutical company reports sales of $96M in third quarter

American Red Cross, Greater Cleveland Chapter - American Red Cross, Greater Cleveland Chapter names chairman

American Society of Clinical Oncology - New curriculum seeks to standardize training of cancer physicians worldwide

Amgen Inc. - Technique provides a simple way to create hypoxic/ischemic conditions in vitro

Anthrax Vaccine - Grant provides $3.5 million for anthrax vaccine study

AntiCancer Inc. - Cells expressing nestin-driven marker model early skin angiogenesis

ArQule, Inc. - Ultrafast analytical method developed for high-throughput parallel synthesis

Arena Pharmaceuticals, Inc. - Biopharmaceutical firm reports loss of $0.54 per share

Artemis Pharmaceuticals GmbH - Research agreement signed with Merck for RNAi-modified mice

Assisted Living - Assisted living in the U.S. costs an average of $2,524 per month

Assisted Reproduction - Winston-Salem woman gives birth to quintuplets

AstraZeneca LP - Data demonstrates the efficacy of CRESTOR in treating elevated cholesterol

Aurora Imaging Technology, Inc. - Company ships first dedicated breast MRI system outside the U.S.

Aventis Pasteur - Dengue infection enhanced by sera from dengue-vaccinated children

Awards - Invacare Corporation's 2003 annual report honored by NAIC

Axonyx, Inc. - Firm retains pharmaceutical special projects group to develop Phenserine

B. Braun - Contract awarded for safety IV catheter device

BSD Medical Corporation - NYU Cancer Center features new hyperthermia system

Bacterial Dysentery - Taiwan warns travelers to be on alert against bacterial dysentery

Baskent University - Higher OPG levels may be associated with IMT in postmenopausal women

Bausch & Lomb - Cataract surgeons get more flexibility with Millennium Advanced Flow System

Baxter Healthcare Corporation - Alpha1-proteinase inhibitor treatment may improve hereditary emphysema outcome

Baxter International, Inc. - Regulatory application submitted in Japan for Advate

Bayer AG - Cipro XR provides rapid symptom improvement in uncomplicated UTIs

Bayer Pharmaceuticals Corporation - Study shows Avelox IV is successful in treating pneumonia in elderly patients

Baylor College of Medicine - Multiple mechanisms are involved in pathogenesis of phenotypes in cardiomyopathy

Beckman Coulter, Inc. - Stem cell monitoring system available to labs on flow cytometry system

Berlex Biosciences - Corin gene is upregulated in hypertrophic cardiomyocytes and failing myocardium

Binax, Inc. - FDA grants clearance for NOW Influenza A & B test

BioStar - Real-time PCR GBS detection test rapidly screens intrapartum vaginal specimens

Biocompare Inc. - Survey expects laboratory product purchases to increase in 2005

Biogen Idec, Inc. - Biotech company reports $132M in net income

Bionomics Limited - Epilepsy diagnostic maker reports strong cash position

Biotech Holdings - Biotech Holdings private placement funding to be applied to diabetes drug launch

Blue Care Network of Michigan - Weight loss program introduced by Michigan provider

Boehringer Ingelheim - Marketing authorization application submitted for Tipranavir

Bone Marrow Transplantation - Bone marrow found for woman seeking South Asian donors

Boston Science Corp. - Paclitaxel induces G1 arrest in arterial smooth muscle cells

Breast Cancer - Women put bra art on display to promote health

Brigham & Women's Hospital - Safety data should not be extrapolated from early to new HIV protease inhibitors

Brigham and Women's Hospital - Dialysis patients half as likely to be treated after a heart attack

Brigham and Women's Hospital - Excessive alcohol intake plus low folate increase risk of colorectal cancer

Brigham and Women's Hospital - Limiting interns' work hours can substantially reduce serious medical errors

Brigham and Women's Hospital - Psychosocial/behavioral variables do not effect 1-year survival after BMT

Bristol-Myers Squibb - Pediatric HIV/AIDS medical centers to be built in Africa

CNR, Pisa - Study indicates need to integrate alternative medicine practice with research

California Institute of Technology - Studies enable analysis of mechanical forces influence during heart development

California Institute of Technology - Systems biology approach may bring new age of predictive, preventive medicine

Callisto Pharmaceuticals, Inc. - American Stock Exchange lists stock of pharmaceutical firm

Canadian Breast Cancer Research Alliance - Gene signatures of transient and acute megakaryoblastic leukemia identified

Cancer & Fertility - Lance Armstrong's former wife summons the courage for her own race

Case Western Reserve University - Nitric oxide and cyclooxygenase-2 interact to generate diabetic eye disease

Catholic University of Korea - Disease and therapy can result in thoracic changes

Catholic University of Louvain - Improved activity of abacavir prodrug due to increased CBV-TP metabolites

Catholic University, Rome - Nonadherence to HAART independently associated with depression

Cell Therapy Research Foundation - Heart cell therapy revitalizes the ailing heart

Centers for Medicare & Medicaid Services - Coverage expansion proposed for cancer patients

Centre National de la Recherche Scientifique - Chronic pneumonia occurs despite immune response to BCG

Chaim Sheba Med Center, Tel Hashomer - Cyoplasmic p53 may enhance the accuracy of HIV-1 RT DNA synthesis

Chiba University - KDEL receptor disturbs endoplasmic reticulum quality control

Chinese University of Hong Kong - SELDI MS plus proteomics scoring distinguishes cancerous from normal cervix

Chiron Corporation - Flu vaccine maker taking action to return to market as reliable supplier

Chugai Pharmaceutical Co., Ltd. - Antibody research to be published in hematology journal

Chukyo Women's University - Receptor polymorphisms associated with midlife weight gain

Clatterbridge Hospital - METH-2 silencing correlates with the advent of non-small cell lung cancer

Cleveland Clinic Foundation - Patients with impaired LV ejection fraction can achieve long-term survival

ClinSource - Use of TrialXS extended into the Asia Pacific region.

Cntr. for Science in the Public Interest - Study links low HDL levels with increased risk of postmenopausal breast cancer

Collaborations - Aetna, Priority Healthcare announce location of new pharmacy partnership

Collaborations - Amedisys selects MedeFinance business intelligence solution

ComPsych Corporation - Increased calls to guidance counselors by parents regarding child depression

Community Research Initiative New England - Quality of life increased with enfuvirtide plus optimized background regimen

Compugen, Ltd. - New method for identifying alternative splicing announced

Coney Island Hospital, New York - Platelet count is an important clue to the diagnosis of malaria

Connetics Corp. - Dermatology-focused pharma reports Q3 earnings per share of $0.10

Connetics Corp. - Velac NDA accepted for filing by the FDA

Continuing Medical Education LLC - U.S. Psychiatric & Mental Health Congress highlights advances in mental health

Corcept Therapeutics, Inc. - CORLUX maker reports increased losses in Q3

Corgentech, Inc. - TF decoy technology company reports Q3 results

Corixa Corp. - EMEA issues positive opinion on hepatitis B vaccine containing Corixa's MPL

Cornell University - Overcrowded and noisy living conditions may contribute to bad health

CuraGen Corp. - Genomics-based pharma reports on Q3, including advances in pipeline

DENTSPLY International, Inc. - Dental products company reports record sales and earnings in Q3

DUSA Pharmaceuticals, Inc. - Phase II Levulan PDT clinical trial for acne

Dalhousie University - Embryonic SC-derived motoneurons develop appropriate transmitter receptors

Datascope Corp. - Monitor maker reports higher first-quarter results

DePuy Spine, Inc. - U.S. FDA approves artificial disc for treatment of low back pain

Dendreon Corp. - Data: Provenge extends survival in patients with advanced prostate cancer

Dental Health - Texas publication selects super dentists for 2004

Diagnostic Products Corp. - Immunodiagnostics company announces increased Q3 sales

Disease Prevention - Malawi: Project encourages female condom use to prevent HIV transmission

Duke University - Animal models help identify mechanisms related to sudden unexplained death

Duke University - Effect of viscosity on the resonance frequency of microbubbles determined

East Tennessee State University - NF-kappaB could be a target for inhibiting development of cardiac hypertrophy

Eclipsys Corporation - Cancer institute installs research, management software system

Elbit Medical Imaging Ltd. - FDA approves ExAblate 2000 system for symptomatic uterine fibroids

Electronic Medical Records - Glendora Digestive Disease Institute selects EMR system from Prime Clinical

Eli Lilly and Company - Pharmaceutical company acquires new compound to treat insomnia

Emory University - Ninein regulates microtubule nucleation

Eon Labs, Inc. - Final approval granted for Citalopram HBr tablets; shipping begins immediately

Epoch Biosciences - Genomic-analysis company reports Q3 loss of $1.2 million

Eurand - Company receives approval to market generic sodium diclofenac

Facilities - Humana adds Sonora Quest Laboratories for outpatient laboratory services

Finance - Community Health Systems reports 18.4% increase in Q3 revenues

Finance - HCA reports increased third-quarter revenues

Finance - Health Grades announces Q3 results: Third consecutive quarter of net income

Finance - Healthcare operator begins trading on New York Stock Exchange

Finance - Horizon Health announces fourth quarter earnings increase of 14%

Finance - IDEXX Laboratories announces third quarter financial results

Flu Vaccine - Arkansas flu shots almost gone

Flu Vaccine - Coconino, Arizona, officials to administer flu shots

Flu Vaccine - Illinois Governor pressures FDA for flu shot plan

Flu Vaccine - Veterans Health Administration cancels flu shot clinics

Fred Hutchinson Cancer Research Center - A new assay improves the timeliness and sensitivity of hepatitis C detection

Frederiksberg University Hospital - Calcium plus vitamin D-3 improves healing of proximal humerus fracture

Free University of Berlin - Titanium, HA-coated implants studied in human bone-derived cells

Fudan University - NMDA receptors in anterior cingulate cortex mediate pain-induced aversion

GWT Technical University - Postprandial hyperglycemia increases risk of cardiovascular disease

GelStat Corp. - Migraine-therapy maker names Nicholas Bluhm as CFO

Gene Research - Researchers find gene to help soybeans repel aphids

George Washington University - Hsp70 protects cells from cell cycle arrest and apoptosis induced by HIV-1 Vpr

George Washington University - Kaposi sarcoma-associated herpesvirus immediate early gene activity explored

Georgia Institute of Technology - Beta1 integrins mediate stratum-derived neural SC adhesion and migration

Georgia Institute of Technology - Poly(lactic-co-glycolic acid) enhances maturation of dendritic cells

German Institute for Human Nutrition - Neurodegenerative disorders associated with diabetes reviewed

Gifu University - Interruption of the Fas/Fas ligand system may treat heart failure

HIV/AIDS Testing - British embassy in Zimbabwe denies racism, staff unrest

Hannover Medical School - Biochemical tests could supplant liver biopsies for diagnosing liver fibrosis

Harvard University - Resistance to obesity in A/J mice not linked to hypothalamic neuropeptides

Health Insurance - Blue Cross Blue Shield of Michigan, Blue Care Network sell new offerings

Health Sciences Group, Inc. - Company gets exclusive worldwide license for cholesterol-reducing nutraceutical

Healthcare Coverage - Companion HealthCare to cover FluMist nasal spray

Healthcare Coverage - New health board approves, rejects hospital proposals

Heart Hospital, London - Mutations in cell adhesion genes provide basis for improved diagnosis

Hebei Medical University - Newly detected hhLIM protein is implicated in heart hypertrophy

Henry Ford Health Systems - New approaches to common methods depict vascular morphology in the brain

Hiroshima University - MOK direct target gene for Cdx2; may be involved in intestinal epithelial cells

Hollis-Eden Pharmaceuticals, Inc. - Acute radiation syndrome therapeutics manufacturer to respond to RFI

Hopital Saint-Antoine, Paris - BEAM with only cytokine support effective in high-risk patients

Hosp. Universitario La Paz, Madrid - Study compares predictive spirometric values to those of other studies

Hospital Central de la Defensa, Madrid - Routine use of chip-mediated diagnostic techniques still in question

Hospital for Sick Children - Chromosome 7 studied for structure and function of the human genome

Hospital of the University of Munster - Study examines molecular mechanisms that predispose hearts to arrhythmias

Human Genome Sciences, Inc. - Drug discovery company announces third quarter 2004 financial results

Hydromer, Inc. - NIH grant to research development of coating to prevent biliary stent occlusion

INSERM Unit 559, Marseille - Hepatic Na+, K+-ATPase reduced after ischemia-reperfusion

INSERM, U258, Villejuif - Combined oral contraceptives affect activated protein C resistance

ISTA Pharmaceuticals, Inc. - Positive results reported from Xibrom study in ocular inflammation

IVAX Corporation - Pharmaceutical company to trade on Warsaw Stock Exchange

Immersion Corporation - Touch feedback technology developer reports third quarter financial results

Immtech International, Inc. - Enrollment completed for DB289 clinical trial in Pneumocystis carinii pneumonia

Immunology - IL-8 involved in cervical dilatation but not in prelabor cervical ripening

In Vivo Medical Diagnostics, Inc. - Prothrombin time monitor under development for use in U.S. clinical trials

Indevus Pharmaceuticals, Inc. - Licensing agreement announced for citicoline therapy for stroke

India Natl. Center Cell Science, Maharashtra - HIV-1 integration sites flanked by potential MARs can act as promoters

Indiana University - Skeletal myoblast grafts generated heterogeneity of Ca2+i ) signaling

InforMedix Inc. - Integrated technology platform for clinical studies presented at PARCS meeting

Injury Prevention - Alliance to create injury prevention program for students

Insmed Incorporated - SomatoKine receives European orphan drug designation

Inst. of Medicinal Molecular Design, Inc., Tokyo - Novel screening method yields acetylcholinesterase inhibitors

Institut de Biologie Structurale, Grenoble - Screening assay devised for inhibitors of mitotic kinesin Eg5

Institute of Zoology, Basel - Jellyfish possess homologues of human vascular endothelial growth factor

Integra LifeSciences Holdings Corporation - DuraGen Plus Adhesion Barrier Matrix issued CE Mark certification

Integra LifeSciences Holdings Corporation - MAYFIELD Infinity Support System to launch in the United States

Intercell AG - Artificial peptide induces Th2 immune response to antigens

International Medical Center of Japan - Single nucleotide polymorphisms lead disease susceptibility

Intuitive Surgical, Inc. - Operative surgical robotics developer reports record third quarter sales

Inverness Medical Innovations, Inc. - Diagnostics company announces third quarter financial results

Invitrogen Corporation - Biotech research company announces 30% increase in third quarter revenues

JPT Peptide Technologies - German biotech expands to United States

Jackson Laboratory - Mouse model yields gene insights

Janssen Pharmaceutical Products, L.P. - Awareness campaign launched after several drug prescribing errors

Japan National Institute Health Science - Ingested Salmonella dose correlates with disease rate

Johns Hopkins Medical Institutions - Hepatitis C virus variants are adequately represented in amplicons

Johns Hopkins Medical Institutions - National survey shows few physicians elected to Congress

Johns Hopkins University - Retardation treatment in the womb may one day be possible

Kansas City Blood & Marrow Transplant Program - Daily IV busulfan + cyclophosphamide for 4 days followed by SCT may be toxic

Karolinska Institute - Hyperinsulinemia and hyperglycemia suppress muscle lipolytic activity

Keio University - Serum ALP, urinary NTX predict 1-year lumbar BMD response to alendronate

Keio University - Tumor reoxygenation compared after carbon-ion and X-ray irradiation

Kensey Nash Corporation - Surgical repair patch receives 510(k) approval

Kimberly-Clark Corporation - Healthcare company reports third quarter results

Kitasato University - Pathway independent of p53 appears to exist related to ulcerative colitis

Kochi University - Membrane protein of Edwardsiella tarda is vaccine candidate

Kyoto University Hospital - Counting immunoassay detects hepatitis markers in whole-blood samples

LAB International Inc. - Clinical trials announced for inhaled cancer pain medication

Labcyte Inc. - Patent awarded for rapid acoustic transfer of nanovolumes in microplate formats

Labopharm Inc. - Canadian biotech reports third quarter results

Legal Issues - New Mexico State board revokes pharmacist's license

Legal Issues - Suicide victim family seeks damages from mental health facility

Legal Issues - Washington man sentenced for stealing cancer patient's identity

Los Angeles Co. Dept. of Health Services - MRSA outbreaks in NICU linked to breast milk

Louis Pradel Hospital, Lyon - Study investigated preexisting apoptosis in donor hearts

Louisiana State University - Estradiol may be beneficial in preventing cardiovascular disease

Louisiana State University of Hlth Science - Abnormal light chains induce divergent phenotypic transformations

Loyola University - The evolutionary history of angiotensinogen suggests nonrandom gene mutations

Lumera Corporation - Peter Biere named chief financial officer at nanotechnology firm

MEDICAL VENTURES CORP. - Medical device company expands product line

MN Council of Health Plans - New nonprofit organization established to improve health care in Minnesota

MPI fur Kernphysik, Heidelberg, Germany - A source of cosmic rays discovered

Mahidol University - Ya-hom inhibits histamine effects on stomach acid and pepsin

Maimonides Hospital - Preexisting diseases influence cytotoxic T-cell response to adenoviral vectors

Malpractice Insurance - Survey shows doctors considering closing their practices

Massachusetts General Hospital - Fewer risks seen for patients participating in early-phase cancer drug trials

Max Delbruck Center for Molecular Medicine, Berlin - Downregulation of corin mRNA may be a mechanism for ANP release in heart failure

Mayo Clinic - Dopamine blocks the effects of vascular growth factors on endothelial cells

Mayo Clinic & Mayo Foundation - Harris-Galante total hip arthroplasty has excellent long-term outcome

McGill University - Support for mental retardation needed

McGraw-Hill Professional - Information technology companies expand strategic alliance

McLaughlin Research Institute - Loci of susceptibility to amyloid precursor protein identified

McMaster University - Trial shows metoprolol CR/XL does not impair glucose and insulin levels

McNeil Consumer & Specialty Pharmaceuticals - U.S. FDA approves use of CONCERTA 72 mg for treatment of ADHD

Medco Health Solutions, Inc. - Study finds expensive medications being used by youngest patients

MediGene AG - Pharma company announces completion of recruitment for skin tumor trial

Medical Action Industries Inc. - Supplier of medical and surgical disposable products reports record revenue

Medical College of Georgia - ROS-induced Ca2+ sensitization is through activation of Rho

Medical Errors - Apology policies for medical mistakes gaining attention

Medical Errors - Doctors may be subject to background checks

Medical-Instill Inc. - Maker of drug delivery devices announces agreement with GlaxoSmithKline

Medics Research, Ltd. - Blood flow monitoring system could reduce risks during surgery

Medicsight - Lesion evaluation tool receives FDA clearance

Medis Diagnostics - Company develops early diagnostic test for lung cancer

Medtronic, Inc. - Medical technology company supports events, activities for disabled employees

Meridian Co., Ltd. - Medical diagnostic equipment company collaborates on cardiovascular study

MetroHealth - Health services company works to detect cardiac arrhythmias in astronauts

Michael J. Fox Fndtn. for Parkinson's Research - Foundation earmarks $3 million to validate Parkinson hypotheses

Michigan State University - HSV-1 VP16 recruits general transcription factors/coactivators to IE promoters

Micromedex - Intravenous drug compatibility database software system introduced

Microscience Ltd. - Antigens expressed in Salmonella vectors using SPI-2 promoter

Mie University - CYP1B1 and PR polymorphisms may be associated with prostate cancer risk

Minot State University - Population increases in obesity appear to be partly due to genetics

Miravant Medical Technologies - Eye health company presented age-related macular degeneration trial results

Misys Healthcare Systems - Information technology company extends product line, announces alliance

Monash University - P-glycoprotein inhibitors plus indinavir might reduce vertical infection

Mt. Sinai Medical Center - Capsule endoscopy aids in detection of small bowel tumors

Mylan Laboratories Inc. - Pharma company reports second quarter financial results

Myriad Genetics, Inc. - Biopharmaceutical company appoints executives

Nanophase Technologies - Nanomaterial developer announces financial results

Nat. Inst. for Public Health & the Env., Bilthoven - Stability of influenza hemagglutinin in vaccine bulk material studied

National Institute on Drug Abuse - Program decreases stimulant use and enhances body image among female athletes

National Research Council Canada - Polypeptides with select binding affinities could direct genes to neurons

Natl. Taipei College of Nursing - Health education intervention helps mid-life women in northern Taiwan

NeuroMetrix, Inc. - Medical device company reports financial results

New York University - E2F1/CDK2 promoter activation requires N- and C-terminal regions of KSHV LANA

New York University - Elder mistreatment in women needs clearer definition, more study

NexMed - Drug delivery company announced acceptance of patent application for Alprox-TD

Norovirus - Number sickened by norovirus at Las Vegas Strip hotel tops 1,200

North Carolina State University - Ancient remedies may hold clues for future medical breakthroughs

Norwood Abbey, Ltd. - Drug-delivery patent granted in Australia

Nottingham Trent University - OX40L exhibits anti-tumor therapeutic efficacy in murine tumor model

Novartis Institute for Tropical Diseases - Partnership announced to develop novel tuberculosis drugs

Nu Skin Enterprises, Inc. - Personal care products company announces 13% year-over-year revenue growth

Nymox Pharmaceutical Corporation - Pharma company granted patent for statin drug treatment of Alzheimer disease

Obstetrics - Michigan women gain improved access to midwifery services

Ohio State University - Substance may improve cancer immune therapy, vaccines

Ohio State University - Utility of antibody-based CLL treatments reviewed

Oklahoma Medical Research Foundation - Nordihydroguaiaretic acid shows promise in murine model

Omega Protein Corporation - Fish oil producer announces completion of health and science center

Omni Medical Holdings, Inc. - Medical billing and transcription company closes $1.6 million in financing

Optiscan - U.S. FDA clears flexible endomicroscope

Oragenics, Inc. - Biotechnology company announces that IND for Oragenics' remains on hold

Orbus Medical Technologies - Vascular disease company concludes enrollment of HEALING II clinical trial

Orchid BioSciences, Inc. - BioSciences company releases financial results

Ortho-Clinical Diagnostics - Diagnostic company launches blood bank educational initiative

Orthofix International N.V. - Orthopedic products company releases financial results

Othera Pharmaceuticals Inc. - Pharmaceuticals company completes $16 million venture capital financing

Our Lady of Mercy Medical Center - Smoking increases risk of colon polyps

Oxford BioMedica - Pharma companies move to next phase of collaboration on cancer targets

Oxford University - New technique detects microcalcifications more reliably

PLC Systems Inc. - Cardiac laser technology company reports financial results

PSS World Medical Inc. - Medical products distributor announced financial results

Pain Therapeutics, Inc. - Biopharmaceutical company presents information on chronic opiod use

Paladin Labs Inc. - Pharmaceutical company reports financial results

Patch International Inc. - Pharma company's Aridol phase III trial achieved endpoints

Patents - U.S. patent granted for care management system

Pediatric Obesity - Eating right a weighty subject for many New Jersey students

Pelikan Technologies Inc. - Hand-held diagnostics company closes $29.2 million series D financing

Peninsula Pharmaceuticals - U.S. FDA grants fast track designation for Doripenem

Peregrine Pharmaceuticals, Inc. - Pharma company provides Tarvacin IND update

Perot Systems Corporation - Information technology company releases system for health plan administration

Personnel - Bluestar Health names James D. Weiss to lead preventative care program

Personnel - Connecture, Inc., names Daniel Maynard new CEO

Personnel - Delta Dental of California names Marland Taylor VP of systems development

Personnel - GTESS appoints Dan Contilli and Jim Gallagher regional sales directors

Pfizer Inc - Pharma company names president of global manufacturing

Pharmacopeia Drug Discovery, Inc. - Strategic alliance formed for metabolic disease drug development

Policlinico A. Gemelli Hospital, Rome - Noninvasive wearable heart care offers continuous monitoring

Premier, Inc. - U.S. FDA selects hospital database for two drug utilization contracts

Princess Margaret Hospital, Toronto - Phenotypic karyotype markers identified in AML with t(8;21)

Purdue University - Novel immunoassay facilitates cytochrome P450 quantification

Purdue University - Rapid immunoassay detects Salmonella Enteritidis in poultry

Queen Margaret University College - Pitfalls of nutritional screening in injured obese patients outlined

Queen Mary's Hospital, Kent - Non-invasive ventilation use in surgical patients characterized

RIKEN - Selective heparanase inhibitors halt cancer metastasis

Refractec Inc. - Research shows NearVisionSM CK is nation's leading nonlaser refractive procedure

Roche Oncology - More testing methods OK'd to select patients who may benefit from Herceptin

Royal Adelaide Hospital - Bosentan improves quality of life, prognosis for PAH patients

Royal Bournemouth Hospital - Effects of rheumatoid arthritis and age on autonomic CV reflex are not additive

Rush University - Black cohosh may trigger autoimmune hepatitis

Russian Academy of Medical Sciences - CD27-negative CD4 T cells produce IFN-gamma upon mycobacteria challenge

RxAmerica - Pharmacy benefit manager among Utah's Top Revenue Growth companies

RxHub LLC - IT company, electronic prescription data provider reach services agreement

Schering-Plough - Two hepatitis C studies with PegIntron plus Rebetol therapy initiated

Scott Edelstein - Lou Gehrig disease targeted by 'Curt's Pitch for ALS' program in Massachusetts

Selective Micro Technologies - U.S. FDA allows use of chlorine dioxide antimicrobial for fruits, vegetables

Serologicals Corp. - Companies ink agreement for new ES cell tissue-culture media

Sigma-Aldrich Corporation - Life sciences company introduces plasmid DNA isolation method

Smoking - Nevada petition would restrict smoking in public

Sontra Medical Corporation - Initial human clinical results of transdermal vaccination study 'promising'

St. Savas Hospital, Athens - Novel Bcl-2 family gene associated with progression of colon cancer

St. Vincent's Institute, Fitzroy - CD4+ cell loss in T-tropic HIV-1 infection is not directly mediated by apoptosis

Stanford University - Telomerase maintained in self-renewing tissues during serial regeneration

State University of Ghent - Regions in fimbrial adhesin FaeG suggest donor strand mechanism

State University of New York, Buffalo - 2-Methoxyestradiol inhibits proliferation of normal and neoplastic glial cells

State University of Rio de Janeiro - Major effect of enalapril is mediated by increased density of vessels

Statens Serum Institute - Study: Recurrent UTI caused by E. coli strain causing preceding UTI

Stem Cell Research - California voters approve spending on stem cell research

Sunrise Senior Living Inc. - Senior living facilities operator praises New York's new assisted living law

SurModics, Inc. - David Wood named VP, GM of medical device company's drug delivery business unit

Synthetech - Drug development company board elects Hans C. Noetzli as new director

Taleghani Hospital, Tehran - High prevalence of parental consanguinity in infants with permanent CH

Talwar Research Foundation - Luteinizing-hormone-releasing-hormone causes prostatic atrophy

Taratec - Richard Riegel named VP of sales by life sciences consultancy company

TargeGen, Inc. - Charles Theuer, MD, PhD, named VP of clinical research, CMO of biotech company

Targeted Molecular Diagnostics, Inc. - Biomarkers of effective Herceptin therapy identified

Technion-Israel Inst. of Technology - Three new drugs could shake off the (brain) rust

Teranode Corporation - Software for life sciences study and research launched

Teva Pharmaceutical Industries - Agilect improves Parkinson symptoms without worsening other adverse effects

Texas Back Institute - Center for artificial disc replacement surgery to open in Texas

ThermoGenesis Corp. - Biotech company submits FDA application to market blood component separator

Third Military Medical University - Cyclooxygenase-2 expression aligns with transitional cell carcinoma invasion

Thomas Gauly - Company updates clinical program for chronic obstructive pulmonary disease drug

Tobacco Use - Colorado residents approve quadrupling tobacco tax for healthcare

Tokyo Metropolitan Inst. of Medical Science - Recycling nutrients helps babies survive birth

Trachoma - Antibiotic dose may stop leading cause of blindness

Transave, Inc. - Investigational new drug application for cancer drug approved by U.S. FDA

Transkaryotic Therapies - Biopharmaceutical company acquires minority interest in TKT Europe-5S AB

Trestle Holdings Inc. - Henry Ford Health System adopts digital imaging system

Tuberculosis - Oregon Health & Science University gets grant for TB research

Tufts University - Smoke-free workplace laws provide protection impossible to achieve otherwise

U.S. Centers for Disease Control and Prevention - WHO network has played essential role in monitoring polio eradication effort

U.S. Food & Drug Administration - L-carnitine exhibits neuroprotective effect in rats

U.S. Food and Drug Administration - "Supplements" for sexual enhancement contain prescription drug ingredient

U.S. Genomics - New reagents enable efficient detection of known human and mouse miRNAs

U.S. National Cancer Institute - Cancer-altered metabolism linked to cytochrome c oxidase subunit variation

U.S. National Institute of Health - Immigrant mothers and their children benefit from child development education

U.S. National Institutes of Health -  S. epidermidis colonization of indwelling medical devices studied

U.S. National Institutes of Health - Global gene expression profiles determined in HNSCC tumor lines

U.S. National Institutes of Health - OraQuick ADVANCE rapid HIV-1/2 antibody test is sensitive and specific

U.S. National Institutes of Health - Paraoxonase 1 gene changes are not Parkinson disease risk factors in Finland

U.S. National Institutes of Health - Stat5 has distinct functions in cell proliferation, survival, differentiation

UNICAMP - Vancomycin-resistant E. facecalis disseminated between hospitals 100 km apart

UNICAMP, Campinas - Molecular monitoring determines nosocomial dissemination of MSRA

Umea University - The tyrosine kinase inhibitor ZD6474 strikes down glioma growth in xenografts

Univ. of British Columbia - Is the long wait for kidney transplants worth it?

Univ. of California, Davis - Cigarette smoke exposure may result in endothelial dysfunction

Univ. of California, Davis - No link found between intussusception and oral poliovirus vaccination

Univ. of California, Los Angeles - PET reporters monitor activity following gene transfer

Univ. of California, San Francisco - Injection drug users often develop hepatitis C virus superinfections

Univ. of California, San Francisco - Long-term medication and counseling help smokers quit successfully

Univ. of Texas Medical Branch - Sera against ChimeriVax-JE vaccine protects against encephalitis virus

Univ. of Texas, El Paso - Interactions among genes, environment, and control of food intake explored

Universidade Federal do Ceara - Melatonin improves sleep in asthmatics

Universite Victor Segalen, Bordeaux - Mitochondria depend upon ATP synthase to make supramolecular structures

University Clinic, Wuerzburg - Do statins reduce dialysis patients' risk of heart disease?

University College London - Heat shock protein acts as efficient carrier for GnRH vaccine

University College, London - Authors advocate describing heart components as seen in the anatomical position

University of Aberdeen - Candida may mate when the going gets tough

University of Alabama - Anthrax proteins associated with germination and outgrowth identified

University of Alabama - Fiber-mosaic adenovirus lends a new approach to adenoviral targeting

University of Alabama - Once attracted, U.S. minority populations tend to participate in studies

University of Arizona - Thyroid hormone and its analogs modulate the expression of cardiomyocyte genes

University of Basel - Drug electrophoresis systems with contactless conductivity detection devised

University of Birmingham - Multi-parameter flow cytometry used in E. coli study

University of Bologna - New risk factors for endocarditis have emerged

University of Bologna - Potential role seen for Bifidobacterium in the intestinal degradation of oxalate

University of Bristol - Scientists find key to unlock body's own cancer defense

University of California Los Angeles - Formaldehyde-induced DNA adducts biomarkers of nasal cell formaldehyde exposure

University of California, San Diego - Spinal PAR stimulation induces thermal hyperalgesia

University of Cambridge - Insulin-like growth factor complex improves insulin sensitivity in diabetes

University of Cincinnati - Adenomatous polyposis coli gene isoforms curtail cancer cell growth

University of Edinburgh - HIV-infected CD8 lymphocytes generated through infection of activated CD8 cells

University of Florida - Models of sex differences in opioid analgesia inconsistent

University of Florida - Wound healing response characterized in rats

University of Freiburg - The membrane anchor domain of hepatitis C virus NS5A has unique functions

University of Gottingen - Iron metabolism is modified by regular LDL apheresis treatment

University of Groningen Hospital - 111In-DTPA-trastuzumab suitable for clinical use

University of Guelph - Insulin stimulates fatty acid transport by regulating expression of FAT/CD36

University of Helsinki - DNA vaccine plus booster protects against Chlamydia pneumoniae

University of Hong Kong -  Streptococcus pneumoniae serotype distribution in Hong Kong determined

University of Hong Kong - Hepatitis B virus DNA in the liver correlates with extent of liver injury

University of Kentucky - Renin-angiotensin system activated in rats with obesity and hypertension

University of Konstanz - Genetic defects in acyl-CoA dehydrogenases influence enzymatic stability

University of Liege - Novel variants of the ADAMTS2 gene mark Ehlers-Danlos syndrome Type VIIC

University of Lille 2 - FXR may be a target for drugs to treat dyslipidemia and cholestasis

University of London Imperial College - Slow skeletal troponin T gene may contribute to myocardial dysfunction

University of Louisville - Hypoglycemia in type 2 diabetes reviewed

University of Manitoba - Beneficial effects of ACE inhibitors is due to renin-angiotensin blockade

University of Miami - Gene mutations alter myocardial performance via changes in Ca2+ sensitivity

University of Miami - Report reviews evidence implicating NO in the pathophysiology of heart failure

University of Minnesota - Obesity increases older women's risk of acute myelogenous leukemia

University of Montreal - Endothelin-1 impaired beta-adrenergic dilation of resistance coronary vessels

University of North Carolina - HIV screening inadequate in North Carolina jails

University of North Carolina - Mice expressing defective human factor IX aid hemophilia B research

University of Nottingham - Intragastric gelation can increase feeling of satiety in humans

University of Oxford - Fas ligand overexpression spawns inflammation in the central nervous system

University of Padua - Minimal model estimation of insulin sensitivity from oral test validated

University of Pennsylvania - Method yields endothelial RNA to facilitate studies of spatial gene regulation

University of Pennsylvania - Study reveals critical care use in serious illness

University of Pisa - Reduced dilation in the brachial artery is related to renal failure severity

University of Pittsburgh - Electroporation augments TGF-mediated healing in the wounds of diabetic mice

University of Pittsburgh - Factor IX replacement postpartum may prevent bleeding in women with deficiency

University of Pittsburgh - Viscoelastic response changes in urinary bladder after spinal cord injury

University of Puerto Rico, San Juan - Physically active HIV-infected persons have higher life satisfaction

University of Queensland - Atorvastatin causes a greater reduction in LDL-cholesterol than pravastatin

University of Queensland - ISCOMATRIX adjuvant is suitable for use in anticancer vaccines

University of Sao Paulo - Maternal exposure to diphenhydramine delays fetal CNS, sexual development

University of Sao Paulo - Prenatal cadmium exposure has deleterious effects, rat study shows

University of Southampton - Anti-IgE antibody omalizumab relieves airway inflammation in asthma

University of Southern California -  Mycobacterium avium strains exhibit differential virulence

University of Southern California - Brachytherapy holds promise as treatment for once-debilitating cancers

University of Stuttgart - Antipsychotic-induced changes in global pallidus dopamine levels characterized

University of Szeged - Mirtazapine-induced lymphocyte gene expression altered in Alzheimer patients

University of Tennessee - Crystal structure of Bacillus anthracis DHPS elucidated

University of Texas - Increased pulsatile GnRH levels may be involved in menopausal symptoms

University of Texas, Houston - cis-Pt(II) complex of 3-aminoflavone induces lung tumor apoptosis and necrosis

University of Toronto - Prospective 20-year study finds pregnant women with IBD have healthy babies

University of Toronto - Team discovers possible genetic mechanism behind heart defects

University of Ulm - Development and function of adipose tissue reviewed

University of Ulster - Short-term chemical ablation of GIP receptor causes glucose intolerance

University of Utah - Acridine orange suitable as predictor of DNA damage in sperm

University of Utah - Genetic link suggested in deaths from cardiac valve diseases

University of Utrecht - Mechanism elucidated for bleomycin inhibition of HIV-1

University of Vermont - Role of cardiac myosin binding protein-C on myocardial stiffness was examined

University of Veterinary Medicine - Squalene adjuvant better than aluminum hydroxide in rabies vaccine

University of Washington - Fetal alcohol syndrome prevention efforts working in Washington state

University of Western Australia - Human disease outbreaks are bioindicators of ecologic well-being

University of Wisconsin - Microfluidic system developed for large DNA molecule arrays

University of Zurich - Control parameters for dendritic cell-T cell interaction determined

University of Zurich Hospital - Diagnostic utility of multi-detector row CT imaging reviewed

VITAS Healthcare - End-of-life care provider announces executive promotions, organizational changes

VNUS Medical, Technologies, Inc. - Radiofrequency generator for vein reflux, varicose veins treatment introduced

Vanderbilt University - Antisense targeting of anti-apoptosis proteins radiosensitizes lung cancer

Varian, Inc. - Lab-based oral fluid drug testing device introduced

Viactiv - Chewable multivitamin introduced

Vita Salute University - CLOCK gene variations may influence clozapine-induced diurnal sleepiness

Vital Images, Inc. - 3D imaging software company signs agreement to integrate CT colon CAD technology

Wake Forest University - Early VEGF supplementation ameliorates cavernosal ischemia in rabbit models

Wake Forest University - Electroconvulsive therapy improves mood, quality of life

Washington University - Review focuses on pathways involved in regulating myocardial energy metabolism

Watson Pharmaceuticals, Inc. - Specialty pharmaceutical company creates new positions in senior management

Wayne State University - Studies suggest green tea/tea polyphenols lower cancer risk/inhibits tumors

West Nile Virus - Human West Nile cases now total 101

Westfalische Wilhelms-Universitat, Munster - Disturbances in protein phosphatases may cause or aggravate cardiac diseases

WinningHabits - Southern Methodist University receives 'Champions in Health' award

World Health Alternatives, Inc. - Medical staffing company signs intent letter to purchase assets of staffing firm

World Population - United Nations report says world population could be 9 billion in 2300

Yale University - Hospitalization and restricted activity can lead to disability among elderly

Yale University - Lower level of education can impede recovery in elderly after hospitalization

Yokohama City University - Laser spray dissociates non-covalent bonds without harming molecular subunits

Yonsei University - Burch colposuspension outcome compared with and without abdominal hysterectomy

Yonsei University - Meta-analysis finds glutathione S-transferase M1 status a potential risk factor

Yonsei University - Peptide mimotopes of N. meningitidis polysaccharide described

Zhejiang University - Bonding of glass microfluidic chips at room temperature achieved

Zuellig Botanicals, Inc. - Nutraceuticals company signs distribution deal with PIVEG

igeneon - Guenter Schirmer, MD, named medical director by drug developer

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