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Erasmus University

Late thrombosis reported in drug-eluting coronary stent recipients

Published in Medicine and Law Weekly, December 10th, 2004

Several cases of potentially fatal late thrombosis have been reported in drug-eluting coronary stent recipients.

"Although the safety profiles of coronary stents eluting sirolimus or paclitaxel do not seem to differ from those of bare metal stents in the short-to-medium term, concern has arisen about the potential for late stent thromboses related to delayed endothelialization of the stent struts," scientists in the Netherlands explained.

E.P. McFadden and colleagues at Erasmus Univeristy presented "four cases of angiographically-confirmed stent thrombosis that occurred late after elective implantation of polymer-based paxlitaxel-eluting (343 and 442...

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