Medicine and Law Weekly

Merck Institute of Aging & Health - Report on aging and health in American finds unhealthy diets, lack of exercise

Mergers and Acquisitions - Henry Schein acquires Barton-Cyker Dental Supply, Inc.

Meridian Bioscience, Inc. - Biosciences company updates financial guidance

Michigan State University - IL-6 greater in preadipocytes than adipocytes of 3T3-L1 cells

Microbix Biosystems Inc. - Urokinase product ThromboClear entering manufacturing stage

Micromet AG - Biopharmaceutical company receives IND designation antibody MT201

Military Medical College II - Co-expressed genes in virus-driven therapy block glioma invasion

Mississippi Baptist Medical Center - Hospital achieves gold seal and disease specific certification from JCAHO

Mt. Sinai Hospital, New York - Technique is rapid, safe, and effective for treatment of bifurcation lesions

Mt. Sinai School of Medicine, New York - Ubiquitin-like modifier required in Caenorhabditis elegans

Myocardial Infarction - Heart attack risk especially high for women with diabetes

NIR Diagnostics Inc. - Near-infrared instruments developer announced financial results

Nagasaki University - Macrolide antibiotics induce apoptosis of human peripheral lymphocytes

National Association of Chain Drug Stores - Chain drug store associations VP Lee L. Verstandig comments on discount card

National Cancer Center, Tsukiji - NCI Common Toxicity Criteria is appropriate in toxicity evaluation of RIST

National Cardiovascular Center Research Inst. - New treatment offers marked improvement in deadly hypertension

National Cheng Kung University - Novel microchip system facilitates quantitative protein analysis

National Taiwan University Hospital - Phenytoin dosages for epilepsy correlate with CYP2C9/CYP2C19 polymorphisms

National Univ. of Ireland, Cork - Conjugated linoleic acid appears to slow bone resorption in ovariectomized rats

National University of Singapore - BMI may not be appropriate measure of obesity in Asian population

Natural Products - Presentation on green tea's ability to combat cancer made at oncology conference

Natural Resources Defense Council, San Francisco - Health impacts requires aggressive efforts to mitigate environmental problem

NeighborCare, Inc. - Institutional pharmacy provider announces financial results

NeoPharm, Inc. - Tumor targeting compound clinical trial results presented at conference

New York Medical College - Dietary potassium intake regulates the response to adenosine

New York University - Transgenic marker lines enable manipulating the pacemaking and conduction system

New York-Presbyterian Hospital - Utility of vagus nerve stimulation elucidated

Northwestern University - Increased endocytotic pathway-mediated A beta 42 secretion in apoptosis

Northwestern University Feinberg School Medicine - High early toxicities noted in HSCT for immune-mediated diseases

Novartis Respiratory Research Center - Mediation of mucin secretion from human bronchial epithelial cells reported

Novogen Limited - Glycotex Inc. receives additional capital for development of Glucoprime

Nutrition - Strict diet can help fight diseases like Alzheimer, E.U. scientists say

Obstetrics - Racial discrimination may contribute to premature births and low birthweight

Ohio Department of Health -  S. enterica serotype typhimurium outbreak linked to raw milk consumption

Ohio State University - Myocardial protection by hyperthermia may occur via HSP90-mediated NO production

Ohio State University - Pain reliever may help treat life-threatening childhood disease

Ohio State University - Rotational X-ray angiography offers less radiation exposure and contrast volume

Ohio State University - Stronger therapy better for AML with normal genetics

OpGen, Inc. - Biotechnology company announces new chief executive officer

Oral Health - Dental plaque linked to pneumonia in hospitalized elderly

Oregon Health and Science University - Interferon-induced depression is not associated with thyroid dysfunction

Ortek Therapeutics Inc. - Pharma company introduces new dental cream for sensitive teeth

Osaka City University - Apigenin degrades HIF-1 alpha protein to staunch angiogenic growth factor

Osaka General Medical Center - Spatial dispersion of QRS duration is a prognostic marker of mortality

Osaka Prefectural Police Headquarters - Flavin-containing monooxygenase mediates selegiline N-oxidation

Osaka University - A protein in breast milk helps prevent and treat deadly neonatal enterocolitis

Osaka University - SOX and POU factors interplay in Nestin gene regulation

Otsuka Pharmaceutical Co., Ltd. - Aripiprazole mechanism of action elucidated

Oxford University -  Drosophila PP1 beta regulates nonmuscle myosin

Palatin Technologies, Inc. - European patent granted for sexual dysfunction medication

PeaceHealth - University to examine physician training opportunities, staffing issues

Peninsula Medical School, U.K. - Parents failing to recognize obesity in their children

Personnel - Cain, Ryan elected to the board of directors of SCAN Health Plan

Personnel - David Dennis named managing director of Pacific Venture Group

Pharmaceutical Technology Congress - Pharmaceutical technology congress announced

Pharming Group N.V. - Pharma company announces results of study with human lactoferrin

Premier Pigments - Permanent pigments producer arranges medical treatment allergic reactions

Pri-Med Institute - Survey finds obesity remains untreated by primary care physicians

Prince Wales Hospital - Main mode of SARS transmission through droplet spread and close/direct contacts

ProBioGen AG - Collaboration established to optimize new generation of bioreactors

Public Health - Drivers admit to experiencing road rage

Pulmatrix - Nose spray may slow spread of germs

Purdue University - Folate-conjugated liposomes target macrophages associated with ovarian cancer

QuantumBit Induction Technology Inc. - Medical technology company readies to acquire Biodyne

Recom Managed Systems, Inc. - Diagnostic devices company announced Model 100 completed safety testing

Revivicor, Inc. - Geron licenses nuclear transfer technology

Rigel Pharmaceuticals, Inc. - Clinical trial results of oral hepatitis C RNA polymerase inhibitor released

Roche - Pharma companies to codevelop PDE4 inhibitors for vascular diseases

Roche - Study to examine efficacy of hepatitis C treatment in Latinos announced

Rockefeller Foundation - Shortages of health workers threaten health initiatives, Rockefeller study shows

Rush University, Chicago - Compliance with guidelines improves prognosis, regardless of risk score

SCAN Health Plan - Health plan receives grant to expand volunteer action in aging program

SCHWARZ PHARMA - Lacosamide data presented, called effective and well-tolerated antiepileptic

SDA Enterprises - Hunger intensity changes after a meal replacement bar for weight control

SRI/Surgical Express, Inc. - Surgical supply company names chief executive officer

STD Manufacturing, Inc. - OEM medical device announces sale of AngioLink

Schering AG - Approvable letter for new oral contraceptive YAZ issued in United States

Scientific American - New magazine exploring mysterious workings of the brain debuted

Semmelweis University of Medicine - Dystrophin expression mapped in rat brain

Seoul National University - Glimepiride determined in human plasma using HPLC with column-switching

Shinmatsudo Central General Hospital - Pioglitazone reduces arterial stiffness in diabetic nephropathy adults

Smoking Addiction - Anthem, CorVasc collaborate to help Indiana kick the smoking habit

Smoking Cessation - HealthMedia announces results of smoking-cessation study

Sorenson Media - Developer of communication technology for disabled gets rights advocates award

St. Louis University - Partial urethral transection fixed by resection of transvaginal tape

St. Mary's Hospital, Seoul - Early prediction of molecular remission by monitoring BCR-ABL transcript levels

Stanford University Medical Center - Young volunteers sought for study to test if infant rash cream prevents asthma

Starion Instruments - Medical instruments technology recognized by laparoendoscopic surgeons' group

Stress - Cigna Behavioral Health's new online program confronts stress

Sun Health Research Institute - DNA damage caused by altered uracil incorporation produces neuron apoptosis

Swissray International Inc. - Medical imaging company introduces several radiography products at conference

Synta Pharmaceuticals Corp. - Small molecule-focused company announces closing of $80 million financing

Tech Museum - Dr. Ashok Gadgil receives Tech Museum $50,000 Affymatrix Health Award

Technical University of Munich - Impaired fibrinolysis in obesity examined

Technical University of Munich - TLR-induced macrophage transcriptional activation characterized

Teva Pharmaceutical Industries Ltd. - Generic drugs developer gets U.S. FDA tentative approval for anticonvulsant drug

Texas A&M University - Citrus shows promise for certain childhood cancer

The Scripps Research Institute - Mercury contamination screening method in biological samples introduced

Thomas Jefferson University - Novel CD8 DE loop peptide analog prevents CD8-mediated graft-versus-host disease

Threshold Pharmaceuticals Inc. - FDA grants Fast Track status to glufosmaide for metastatic pancreatic cancer

Tobacco Use - States don't meet CDC-set spending levels for anti-smoking efforts

Tohoku University - Case reported of vaginal primary mucosa-associated lymphoid tissue lymphoma

Tohoku University - Vasohibin is a negative regulator of tumor angiogenesis

Tokyo Medical University - Device provides both ankle-brachial pressure and pulse wave velocity readings

Trestle Holdings Inc. - Digital imaging, telemedicine firm announces digital pathology service platform

Tufts University - Associations studied between vitamin K biochemical measures and BMD

Tulane University - A mutation that causes exon skipping produces non-ocular Stickler syndrome

Tulane University - Fat tissue contains cells that may treat central nervous system defects

U.S. Air Force - Commercial mosquito trap and gravid trap oviposition media evaluated

U.S. Centers for Disease Control & Prevention - Susceptibility of Anopheles farauti to Plasmodium tested

U.S. Centers for Disease Control and Prevention - CDC updates status of HIV testing in U.S.

U.S. Centers for Disease Control and Prevention - Leukocyte antigen alleles linked to viral load in HIV seroconverters

U.S. Centers for Disease Control and Prevention - Prostate leading newly diagnosed cancer among men; breast cancer leads for women

U.S. Food & Drug Administration - FDA-approved neurologic devices for use in children reviewed

U.S. Food and Drug Administration - Agency finalizes new rules for "good tissue practice"

U.S. Food and Drug Administration - FDA announces enhancement to isotretinoin risk management program

U.S. National Cancer Institute - HPLC-MS method measures endogenous ketolic estrogen metabolites in human urine

U.S. National Naval Medical Center - Pseudoporphyria resulting from voriconazole use reported

U.S.VA National Center for Patient Safety - U.S. VA patient safety division developing patient safety curriculum

UPMC Presbyterian - Genetic testing many play key role in management of pancreatitis

United Disability Services - Nonprofit 'Accessing Independence' organization created in Pennsylvania

Univ. of California, San Diego - Regulated production of chemokine CCL28 in colon epithelium described

Univ. of Texas Medical Branch - Mechanisms of action of the implantable gastric stimulator for obesity

Universidad Central del Caribe, Bayamon - Counseling plus case management reduces HIV risk behaviors in IVDUs

Universidade Federal do Rio Grande do Sul - Retrieval does not induce reconsolidation of inhibitory avoidance memory

Universite Catholique de Louvain - IGF-I decline in induction of atrogin-1/MAFbx in diabetes studied

University Health Network, Toronto - Raf/MEK/ERK pathway block sensitizes AML cells to lovastatin-induced apoptosis

University Hospital Brno - Limb girdle muscular dystrophy type 2A patients harbor calpain3 mutations

University Hospital Navarre - Bone measurement techniques compared for children and adolescents

University Hospital North, Marseille - Terlipressin can be effective to restore mean arterial pressure in septic shock

University Medical Center Utrecht - An individual's behavioral traits may influence cancer progression

University Medical Center Utrecht - Effects of atorvastatin on fasting plasma, marginated apolipoproteins reported

University Medical Center Utrecht - Rodent behavior signals joint destruction levels after arthritis induction

University at Buffalo - Two-fisted assault on dopamine transport system may be foundation of PD

University of Alberta - In-solution digestion improves mass spectometry lipid raft detection

University of Alberta - Proinsulin secretion linked to graft function after islet transplant

University of Alberta - Student nurses need better understanding of poverty-stricken patients

University of Barcelona - Abnormal DV flow pattern may signal cardiac defects in normal-karyotype fetuses

University of Birmingham, U.K. - Disoriented T cells cause liver disease

University of Bristol - Copper impairs endothelium-dependent relaxation of aortae in diabetes

University of Cagliari, Sardina - Reduction of uric acid beyond a threshold does not affect endothelial function

University of Calgary - Uterine secretion of ISP proteins regulated by progesterone and estrogen

University of California Los Angeles - Study investigated muscle mechanoreceptor control

University of California San Diego - Mitogenesis is mediated by TRPC4 expression and activity

University of California, Davis - Thermoreversible hydrogel scaffolds used for articular cartilage engineering

University of California, San Diego - TRPC1 overexpression enhances of pulmonary vasoconstriction

University of Cambridge - Neural contributions to motivational control of appetite in humans examined

University of Cambridge - Recurrent chromosome breakpoint at NRG1/Neuregulin 1/Heregulin gene studied

University of Colorado - Novel LC-MALDI-MS analysis method developed

University of Copenhagen - Exercise decreases cerebral metabolic ratio when a conscious effort is required

University of Delaware - Egr-1 antisense molecules interfere with fear conditioning in rats

University of Durban-Westville -  Sclerocarya birrea extract is analgesic and anti-diabetic

University of Erlangen-Nurnberg - Feedback-based laser system shows promise for tissue-specific cutting

University of Florida - Central leptin gene therapy shows promise for diminishing obesity

University of Florida - Lentiviral vectors bear clones that offer long-term ACE2 secretion

University of Florida - Novel gene transfer prevents enlarged heart, cardiac fibrosis

University of Georgia - Pasteurization destroys Listeria monocytogenes in peanut and chocolate products

University of Georgia - The word mutation generates negative connotations in many people's minds

University of Glasgow - Poly(L-proline) helix demonstrated in the N-terminal region of a prion protein

University of Groningen - Factors influencing isolation of functional pancreatic islets examined

University of Hamburg - High-dose chemotherapy relapse is risk factor for treatment-related MM mortality

University of Helsinki - LCAT induces estradiol esterification in HDL, boosting antioxidant potential

University of Innsbruck Hospital - NK suppression related to circulating CD34 cell number during PBPC apheresis

University of Iowa - Current treatment strategies for respiratory infections and asthma reviewed

University of Iowa - Physical activity may reduce risk of preeclampsia

University of Iowa - The brain renin-angiotensin system contributes to the pathophysiology of CHF

University of Liege - Role of heat shock factor 1 in inhibition of NF-kappa B pathway studied

University of Linz - Imaging details, pathological differences of red blood cells seen in lupus

University of London Imperial College - Infection control measures rapidly controlled Norovirus hospital spread

University of Louvain - Sildenafil influences gastric sensorimotor function in humans

University of Maastricht - Matricellular proteins may have crucial functions in hearts coping with stress

University of Manitoba - Avian reovirus mutant has major core protein lesion and is defective in assembly

University of Massachusetts - Gateway-compatible yeast one-hybrid system developed

University of Medicine & Dentistry of New Jersey - Etanercept treats psoriatic arthritis and psoriasis in hepatitis C cases

University of Michigan - Inhibition of human cytomegalovirus replication involves three mechanisms

University of Michigan Health System - U of Michigan gets $44 million gift to speed up search for type 1 diabetes cure

University of Milan - Lercanidipine may inhibit macrophage functions involved in plaque stability

University of Milan - Training improves DL_CO in chronic heart failure

University of Minnesota - Geographic distribution of resistant uropathogenic E. coli in U.S. outlined

University of Missouri - Drug delivery system with EDTA is safe intravaginal barrier device

University of Montpellier - Muscle biopsy used in the analysis of the dystrophin gene

University of Montreal - Study characterized impact of hypertrophy on mitochondrial NADP⁺-ICDH

University of Munster - Biotechnical innovations improving engineering of extracorporal bone tissue

University of Naples - Left atrial function is a strong predictor of atrial fibrillation development

University of Nevada - Human hepatocytes formed by human hematopoietic stem cells in sheep

University of New Mexico - Growth in human fibroblasts repressed by ionizing radiation

University of New South Wales - Basic movements classified using triaxial accelerometer

University of Nijmegen - Cytochrome c oxidase biogenesis in a patient with a COX10 mutation

University of Notre Dame - Glutaraldehyde-linked bovine Hb-based blood substitute increased oxygen affinity

University of Oslo - Predominant subgroup of CCR7^- T cells identified

University of Parma - Yeast killer toxin-like antibodies possess therapeutic potential

University of Pennsylvania - Autocrine Epo signaling inhibits hypoxia-induced apoptosis in cancer cells

University of Pennsylvania - Novel techniques allow molecular tailoring of chemotherapy

University of Pennsylvania - PAL-E-reactive vimentin exhibits unique functions in the blood vasculature

University of Pennsylvania - Radiological features of treatment complications reviewed

University of Pittsburgh - HMG-CoA reductase is a target of agents that staunch angiogenesis

University of Pittsburgh - Liver C-JUN N-terminal kinase activated by tissue hypoxia in hemorrhagic shock

University of Queensland - Hepatic disposition kinetics of propranolol isomers characterized

University of Rochester - PGE₂ inhibits chondrocyte differentiation through PKA and PKC signaling

University of Roma La Sapienza - Disruptive effect of ryanodine receptors in mouse spermatogenic cells reported

University of Roma La Sapienza - Thyroid hormones regulate DNA-synthesis and cell-cycle proteins

University of South Carolina - Management of infected synthetic grafts after abdominal sacrocolpopexy reviewed

University of Southampton - New anti-idiotype antibody binds rituximab on surface of lymphoma cells

University of Teheran - Binding of theophylline and adenosine deaminase characterized

University of Tennessee - Interleukin-1 receptor antagonist counteracts HSV-related corneal inflammation

University of Tennessee - Intravascular pressure elevates wall tension in newborn cerebral arteries

University of Texas - Biomarkers may characterize functions of polymorphic DNA repair genotypes

University of Texas - Peridomestic mosquito adaptation mediates dengue emergence from progenitor DENV

University of Texas, San Antonio - Elevated liver injury markers indicate increased type 2 diabetes risk

University of Texas, San Antonio - Exercise increases glycogen synthase activity in type 2 diabetes

University of Tokyo - Expression imbalance maps can improve genomic analysis

University of Toulouse - Hippocampal CA3-region is crucial for memory consolidation

University of Tsukuba - A novel assay monitors hepatitis C patients for blood ribavirin levels

University of Tubingen - Apoptosis-inducing factor orthologue regulates apoptosis in yeast

University of Udine - Carbohydrate requirement during exercise in diabetic patients studied

University of Virginia - Osteoblast adhesion to common biomaterials regulated through integrin binding

University of Washington - Group blocks formation of toxic protein clumps seen in HD

University of Washington - Metabolism of cyclosporine A by kidney CYP3A5 characterized

University of Washington - Relapse is major cause of treatment failure after BMT in pediatric AML

University of Wisconsin - Future selection practices may match specific recipients to specific donors

University of Wisconsin - Green tea polyphenols thwart prostate cancer development at multiple levels

University of Zagreb - Honey-bee products in cancer treatment and prevention

VTT Technical Research Center - International research team identifies gene that promotes prostate cancer

VU University Medical Center, Amsterdam - Tailored and targeted therapy possible in pediatric acute myeloid leukemia

Vaccines - Texas researchers to begin testing vaccine against ricin in humans

Valeant Pharmaceuticals - Pharmaceutical company sells Spain-based manufacturing operations

ValueOptions - Behavioral healthcare firm wins award for 'Achieve Solutions' web site

VaxGen, Inc. - Biopharm company enters agreement to raise $40 million through common stock sale

Ventracor Limited - Medical device company to submit IDE application to FDA

Verispan - Healthcare informatics company launches pharmaceutical data access sales system

Virginia Commonwealth University - Eliminating racial disparities would save more lives than technological advances

Virginia Commonwealth University - Study examined the cardioprotective role of Ca²⁺-activated K⁺ channels

VisiJet Inc. - Opthalmic medical devices company reports third quarter 2004 financial results

Vital Living Inc. - Neutraceutical company reports financial performance for third quarter 2004

W. L. Gore & Associates, Inc. - ArteriA Medical Science Inc. assets acquired

Wake Forest University - Amount of visceral adipose tissue is heart attack risk factor in older women

Wakefield Orthopedic Clinic - Outcome of unicompartmental knee arthroplasty with mini-incision evaluated

Washington University - Molecular partitioning during host cell penetration by Toxoplasma gondii

Washington University - Vaccine for food poisoning possible

Washington University, St. Louis - Diastolic function at rest is a determinant of maximal exercise capacity

Washington University, St. Louis - Study sought to identify ERRalpha-regulated pathways in heart tissues

Watson Pharmaceuticals, Inc. - U.S. FDA approves depression drug citalopram hydrobromide

Weizmann Institute of Science - Microarray analysis of IgG autoantibodies predicts diabetes in mice

WellChoice, Inc. - Insurance company expands broker web portal to allow online renewals, quotes

Westmead Hospital - CD62L+ T cells less responsive to alloantigen stimulation than naive T cells

Wex Pharmaceuticals Inc. - Phase 2a trial of drug for withdrawal in opiate dependent patients initiated

White Electronic Designs, Corp. - Electronics design company reports fourth quarter and fiscal 2004 financials

Women's Bioethics Project - Advisory board for women's bioethics think tank named

World Cancer Research Fund Intl. - Global report on diet, physical activity and cancer enters new phase

World Health Organization - Wider use of antiparasite drugs benefits very young children, pregnant women

World Health Organization - Women and girls need access to AIDS therapies and protection from violence

XTL Biopharmaceuticals, Ltd. - Biotech firm CEO to step down effective from 1 January 2005

Xanodyne Pharmaceuticals - U.S. FDA grants fast track status for drug to treat heavy menstrual bleeding

Yokohama City University - Accumulation of cardiolipin is one of the causes for replicative senescence

Zolaris BioSciences LLC - U.S. patent issued for stabilized bioactive peptides

diaDexus, Inc. - Data demonstrate elevated Lp-PLA2 Levels predict coronary artery disease

eClinicalWorks - Medical records software maker integrates with Antek HealthWare system

eSys Medical Systems, Inc. - Eclipsys to acquire a radiology information-system company

invivodata inc. - IT company named finalist for Red Herring list of most innovative companies