Telos Pharmaceutical
Mutant IL-15/Fc protein prevents development of collagen-induced arthritis
Published in Medicine and Law Weekly, January 7th, 2005
According to a study from the United States and Germany, "It has been suggested that the inflammatory cytokine IL-15 plays an important role in the development of several autoimmune diseases, including rheumatoid arthritis. We have generated a unique lytic and antagonistic IL-15 mutant/Fcgamma2a fusion protein (CRB-15) that targets the IL-15R. In the present study we examined the effects of targeting the IL-15R on the prevention and treatment of collagen-induced arthritis (CIA) in mice and probed the...
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