University of Chicago
Herpes simplex virus UL 41 protein studied, effect on cellular mRNAs revealed
Published in Medicine and Law Weekly, March 18th, 2005
"The UL 41 protein of herpes simplex virus 1 has been reported to mediate the degradation of both viral and cellular mRNAs. Extensive studies on beta-actin and some viral mRNAs were consonant with this conclusion," wrote A. Esclatine and colleagues, University of Chicago.
"In earlier studies, we reported that the UL 41-dependent degradation of cellular mRNAs up-regulated after infection was selective. One class of the up-regulated mRNAs, exemplified by the...
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