Mitsubishi Kagaku Institute of Life Sciences
Data advance knowledge in cardiology research
Published in Medicine and Law Weekly, March 18th, 2005
Study 1: Cardiac abnormalities cause early lethality of jumonji mutant mice.
According to a study from Japan, "Jumonji (jmj) mutant mice, obtained by a gene trap strategy, showed several morphological abnormalities including neural tube and cardiac defects, and died in utero around embryonic day 11.5 (E11.5). It is unknown what causes the embryonic lethality."
M. Takahashi and colleagues of the Mitsubishi Kagaku Institute of Life Sciences continued, "...we demonstrate that exogenous expression of jmj gene in the heart...
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