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State University of New York, Stony Brook

Subcutaneous fat loss not due to accelerated apoptosis in HIV lipodystrophy

Published in Medicine and Law Weekly, April 8th, 2005

Subcutaneous adipose tissue loss is not due to accelerated apoptosis in HIV-associated lipodystrophy.

According to recent research from the United States, "HIV-associated lipodystrophy is characterized by a loss of adipose tissue from the subcutaneous compartment. Previously reported data suggested that this loss of adipose tissue was the result of an increased rate of apoptosis in subcutaneous adipose tissue."

"The present study examined the rate of apoptosis in subcutaneous adipose tissue with a sensitive ligase-mediated polymerase chain reaction technique to amplify DNA ladders," wrote D. Mynarcik and colleagues at the State University of New York...

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