Published in Medicine and Law Weekly, June 24th, 2005
"In spite of advances in understanding the role of the cellular PrP in neural cell interactions, the mechanisms of PrP function remain poorly characterized. We show that PrP interacts directly with the NCAM and associates with NCAM at the neuronal cell surface," wrote A. Santuccione and colleagues, University Hamburg.
"Both cis and trans interactions between NCAM at the neuronal surface and PrP promote recruitment of NCAM to lipid rafts and thereby...
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