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Osaka University

Beta2 -adrenoceptor polymorphisms relate to insulin resistance

Published in Medicine and Law Weekly, September 23rd, 2005

Beta2 -adrenoceptor polymorphisms relate to insulin resistance and sympathetic overactivity as early markers of metabolic disease in nonobese, normotensive individuals.

According to recent research from Japan and the United States, "The genes responsible for insulin resistance are also candidate genes for insulin resistance-related diseases, such as obesity and hypertension. Functional polymorphisms in the beta2 -and beta3 -adrenergic receptors have been reported to be associated with diabetes, hypertension, and obesity. To clarify the relevance of the beta-adrenergic receptor polymorphisms to insulin resistance, we studied their...

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