University of Cambridge
Plasma membrane protein mobility analyzed, role of lipid interaction revealed
Published in Medicine and Law Weekly, October 14th, 2005
"Translocation of a protein to the plasma membrane in response to the generation of polyphosphoinositol lipids is believed to be an important component of cellular regulation, in part because it increases the effective concentration of that protein relative to other proteins in the same membrane by restricting it to a two-dimensional space.
"However," wrote D. Brough and colleagues, University of Cambridge, "such a concept assumes that, once translocated, a protein retains the free mobility it had in the...
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