Medicine and Law Weekly

Ohio State University - Asthma-associated polymorphisms are inversely related to glioblastoma multiforme

Ohio State University - IL-15, but not IL-2, rapidly induces lethal xenogeneic graft-versus-host disease

Oita University - A transcriptional regulatory strategy may achieve neovascularization after cerebral ischemia

Okayama Southern Institute of Health - Exercise intensity of 30% heart rate reserve is recommended for overweight subjects

Okayama University - New data illuminates research in virology

Okayama University - p53 protein transduction therapy facilitates glioma cells' anti-cancer effect

Onmark - Group purchasing organization signs contract with Novartis for Zometa

Optimer Pharmaceuticals, Inc. - Biopharma company names Gorbach chief medical officer, Sr. VP medical affairs

Orion HealthCorp, Inc. - Physician business services provider announces two resignations

Orthopedic Hospital Vienna-Speising - Researchers publish new studies and findings in the area of hip replacement

Orthovita, Inc. - Orthopedic biomaterial developer reports 22% increase in product sales

Osaka University - Neural stem cell factor may control glioma cell proliferation

Osiris Therapeutics, Inc. - Safety milestone reached in stem cell clinical trial for cardiac patients

Osmangazi University, Eskisehir - AIDS-related knowledge in Turkey is high

Othera Pharmaceuticals, Inc. - Phase II trial underway of OT-551 to prevent cataracts after vitrectomy surgery

Oulu University - Valproate increased Ara-C cytotoxicity in acute myeloblastic leukemia cells

Owens & Minor, Inc. - Access Diabetic Supply acquires operating assets, expands customer base

Oxford Center for Diabetes - TNF and LTA variants are unlikely to be involved in type 2 diabetes risk

PBM Pharmaceuticals, Inc. - Animi-3 clinical trial for cardiovascular risk reduction and cognition begins at Tufts University

Pasteur Center, Cameroon - New study finds malaria could play key role in mother-to-child transmission of HIV

Peking Union Medical College, Beijing - MSC transplantation could inhibit LV remodeling and improve heart function

Peking University - KEGG Orthology-based software automates genome annotation and pathway identification

Personnel - Amerigroup Corp. appoints new chief financial officer

Personnel - GTESS appoints new senior vice president and chief revenue officer

Peter MacCallum Cancer Center, Melbourne - New findings in cancer therapy described

Pfizer Global Research & Development - Single 2 g dose of azithromycin microspheres as effective as 7-day levofloxacin course

Pfizer Inc - European approval granted for Revatio to treat pulmonary arterial hypertension

Pfizer Inc - Mutations in the Braf gene predict sensitivity to novel class of cancer drugs

PharmaFrontiers Corp. - Pharma company elects Brooks Boveroux as chairman of the board

Pharmos Corporation - Alan L. Rubino named president, COO of neurology focused pharmaceutical company

PhotoMedex, Inc. - Contract medical procedure provider announces revenues of $7.6 million

Picis - Northeast Medical Center in Humble, Texas, selects emergency department information system

Pluristem Life Systems, Inc. - Biotech company appoints Arnon Nagler to scientific advisory board

Policlinico Umberto 1, Rome - Data advance knowledge in virology research

Pozen Inc. - Pharma company names Dr. Elly Savaluny as vice president

Praecis Pharmaceuticals Incorporated - Biopharma developer reports net loss in third quarter

Procardiaco Hospital, Rio de Janeiro - Autologous bone marrow cells regenerate vascularity in ischemic hearts

Progenics Pharmaceuticals, Inc. - Pharma company reports revenues of $2.8 million

Progenitor Cell Therapy, LLC - Expansion underway at cGMP/cGTP cell therapy manufacturing facility

Pure Protein LLC - Recent findings in vaccines development provide new insights

Qiagen N.V. - Diagnostics company sales increase 9% to $98.7 million

Queensland University of Technology - Dominance should be considered when assessing functional impairment among cancer survivors

Radboud University of Nijmegen - Tumor multifocality identified as prognostic factor for prostate cancer

Radboud University of Nijmegen - Vessel cooptation supersedes angiogenesis in gliomatosis cerebri

Rambam Medical Center, Haifa - Percutaneous tracheostomy complication rates in obese are similar to normal risk patients

Repligen Corporation - Biopharma company reports revenue of $2.8 million

Restless Legs Syndrome Foundation - Survey shows half of Americans unfamiliar with restless legs syndrome

Roche Pharma - U.S. FDA approves erlotinib plus gemcitabine chemo for advanced pancreatic cancer

RocheMedia - Capecitabine plus chemo shown to extend survival of pancreatic cancer patients

Rockefeller University, New York - Disruption of rereplication prevention mechanisms triggers a DNA damage response

Royal Marsden Hospital, London - Resistance of estrogen receptor negative breast cancer to endocrine therapy discussed

Royal Melbourne Hospital - Active-fixation leads should be repositioned if high stimulation threshold lasts 4+ minutes

Royal Victoria Hospital, Montreal - Antithymocyte globulin induction therapy does not affect graft survival

Ruhr University of Bochum - Age at onset of Huntington disease is not modulated by DNase variation

Rural/Metro Corporation - Medical transportation company reports revenue of $140.9 million

SIGA Technology Inc. - Antipoxvirus compound protects mice from lethal orthopoxvirus challenge

SNP Research Center, Kanagawa - Polymorphisms in gene encoding Kruppel-like factor 7 are linked to type 2 diabetes

Saint Louis University School of Medicine - New research may provide means of predicting heart disease in women

Santhera Pharmaceuticals - Collaboration to evaluate idebenone compound SNT-MC17 in Friedreich's ataxia

Schering AG - Pharmaceutical company to divest Mexico chemical production site

Seoul National University - PCK1 polymorphisms are associated with high-density lipoprotein and triglyceride levels

Seoul National University - PPARGC1A polymorphisms are associated with early-onset type 2 diabetes mellitus

Seoul National University - Viral hepatitis treatment prevents glutathione-mediated acute liver injury

Sepracor Inc. - Pharmaceutical company announces intent to reacquire shares of common stocks

Shaheed Beheshti University of Medical Sciences, Tehran - Higher diverse diet could decrease risk for some metabolic disorders

Shanghai University - Inhibition of AF116909 gene expression enhances the differentiation of neural stem cells

Shenyang Pharmaceutical University - Novel elementary osmotic pump developed for multidrug delivery therapy of type 2 diabetes

Shifa International Hospital, Islamabad - Diagnosis with HCV is more stressful than divorce, job loss, and relocation

Shinshu University, Nagano - Hepatitis B virus core and core-related antigen quantified

Showa University, Tokyo - Long-term ursodeoxycholic acid treatment potentiates hepatocyte apoptosis

Siemens Medical Solutions - Clinician portal system earns top honors in KLAS physician/clinician study

Siemens Medical Solutions - Imaging company launches fluoroscopy system to accommodate bariatric patients

Small Bone Innovations, LLC - Multi-use modular hand fixation system launched at hand surgery convention

Somanetics Corporation - U.S. FDA grants 510(k) clearance to expand use of blood oxygen saturation monitor

Sonic Innovations, Inc. - Digital hearing aid company names Westover as president

Sontra Medical Corporation - U.S. Army awards grant to investigate transdermal delivery of dengue vaccine

Soroka University, Beer Sheva - Updated clinical practice guidelines for acute otitis media are released

South Dakota State University - South Dakota university will soon be H5N1 testing center

Spectral Diagnostics Inc. - Disease management company contributes to first sepsis biomarker conference

Spectrum Pharmaceuticals, Inc. - Pharmaceutical company reports 5-month net loss of $5.2 million

Spectrum Pharmaceuticals, Inc. - Phase II study to evaluate satraplatin in patients with metastatic breast cancer

SpineMedica Corp. - Spine devices company forms advisory board to review disc replacement product

St. James's University Hospital, Leeds - Psychosocial difficulties associated with deprivation in cancer patients

St. Jude Medical, Inc. - Medical devices company to acquire Advanced Neuromodulation Systems

St. Luke's-Roosevelt Hospital, New York - Transplant of WAT into mice guards against obesity, insulin resistance and infertility

St. Mary's Hospital, London - Peritoneal nebulizer-delivered treatment prevents postoperative recurrence in rats

Stanford University - Computer-aided detection increases number of cancers found with screening mammography

State University of New York, Buffalo - Daptomycin, linezolid, and quinupristin/dalfopristin used to manage infections

Strauman - Developer of dentistry implants introduces new ceramic material for abutments

Surface Logix Inc. - Biophysical chemistry firm closes $32 million of financing for clinical programs

Surgical Technology - Botox ranks number one for non-invasive cosmetic surgical improvement procedures in the country

Sutura, Inc. - Tom Lindsey named VP, sales and marketing, of California medical device company

SynCardia Systems, Inc. - Artificial heart developer earns Entrepreneurial Company of the Year Award

Sysmex America, Inc. - VA healthcare network awards contract for hematology instrumentation services

Targeted Genetics Corporation - Biotechnology company reports third quarter net loss of $5.7 million

Taunton & Somerset Hospital - AUDIT screen predicts patients at risk of withdrawal symptoms

Telik, Inc. - Small molecule drug developer reports Q3 net loss of $17.9 million

Tempur-Pedic International Inc. - Study shows use of neck pillow reduces snoring and brings sounder sleep

Tercica, Inc. - Endocrine-focused biopharma company reports $11.5 M net loss for third quarter

Teva Pharmaceutical Industries Ltd. - Generic pharmaceuticals company reports third quarter net income of $267 million

Texas A&M University System Health Science Center - FGF2 negatively regulates induction of neuronal progenitors from neural stem cells

Thames Valley Nuffield Hospital, Wexham - Adjunctive Daflon 500 mg accelerates healing

The California Endowment - National standards established for medical interpreting

The Doctors Company - Insurer's perspective on error in surgical pathology practice presented

Thomas Jefferson University Hospital, Philadelphia - Some foods, beverages could hold clues for future diabetes treatment

Thomas Jefferson University, Philadelphia - Metabolic syndrome and diabetes treatment is important for cardiovascular risk control

Tm Bioscience - Test developed for detection of major human respiratory viruses

Tocris Bioscience - Chemical supplier for life science research opens new U.K. laboratory facilities

Tokyo Metropolitan Institute of Neuroscience - Aquaporin 4 expression is enhanced in brains with inflammatory diseases

Tokyo Women's Medical University - Researchers' work adds to imaging body of knowledge

Toronto Western Hospital - Primary caregivers of HIV-infected children do not disclose HIV status to them

Transgenomic Inc. - Provider of research tools closes announced private placement of common stock

Triage Medical Inc. - U.S. FDA grants marketing clearance for cervical spine stabilization devices

Tulane University, New Orleans - Researchers detail new studies and findings in the area of neurology

U.S. Army Medical Research Institute of Infectious Diseases - Real-time PCR targets a unique chromosomal sequence of Yersinia pestis

U.S. Center for Consumer Freedom - 47% of those surveyed believe eating infected chicken can spread avian influenza

U.S. Department of Defense - Army program reduces children's pesticide exposure

U.S. Food & Drug Administration - Antimicrobial resistance is common in Shiga toxin-producing E. coli

U.S. International Epidemiology Institute - Increased BMI is associated with higher risk of pancreatic cancer in men

U.S. National Cancer Institute - Estrogens play important role in early pathologic process towards breast cancer

U.S. National Cancer Institute - Follow-up study confirms that tamoxifen reduces breast cancer risk

U.S. National Cancer Institute - Genetic variants of DNA repair genes may be involved in prostate cancer etiology

U.S. National Health Foundation - Blue Cross of California awards $250,000 grant to improve healthcare access

U.S. National Institute for Occupational Safety & Health - A human mineral dust-induced gene is a cell growth regulating gene associated with lung cancer

U.S. National Institutes of Health - Data advance knowledge in diabetes therapy research

U.S. National Institutes of Health - Microanalytical system determines biochemical milieu of skeletal muscle

U.S. National Institutes of Health - Quiescent neural stem cells can self-renew for over a year and generate multiple cell types

UCB Pharma - Study to measure impact of epilepsy drugs on children's cognitive abilities

ULB, Brussels - CD133-positive cells contain mesenchymal stem cells with high proliferative potential

US Oncology Holdings, Inc. - Cancer services network parent company reports Q3 revenue of $648.3 million

Ultrasound & New Modalities Research - Gas-filled microparticles and sonoporation are effective against tumors

Unilens Vision Inc. - Contact lens company reports increases in sales, royalties, and earnings

Universal Health Services, Inc. - Hospital company reports Q3 earnings, financial impact of hurricane Katrina

Universidad Nacional Autonoma de Mexico, Mexico City - Biotin-dependent regulation of gene expression in human cells is protective

Universidad Nacional Autonoma de Mexico, Queretaro - Prolactins regulate retinal angiogenesis

Universitats-Augenklinik, Mannheim - Macular edema and ischemia are linked to visual acuity after intravitreal triamcinolone dose

Universitatsklinikum Tubingen -  Yersinia vaccine carrier strains induce CD8+ T cell responses

Universite Catholique de Louvain - DNA electrotransfer into skin using high- and low-voltage pulses is reported

Universite Claude Bernard Lyon 1 - HSV-1-derived vectors for gene transfer and gene therapy are reviewed

Universite Francois-Rabelais de Tours - New CD4-CD8 alpha+CD205+CD11b- murine spleen dendritic cell line is established

Universiti Kebangsaan Malaysia, Kuala Lumpur - Palm vitamin E is more potent than alpha-tocopherol in improving dermal wound healing

University College of Dublin - Rho-kinase inhibition alters hypoxia-induced angiogenesis in pulmonary circulation

University Eye Hospital, Bern - Photodynamic therapy benefits patients with ocular disease despite some risk for complications

University Hospital of Catania - New findings in transplant medicine described

University Hospital of Kragujevac - Hyperfractionated radiotherapy and carboplatin/paclitaxel used to treat lung cancer

University at Buffalo - Statin increased stem cell concentration that may aid heart repair

University of Alabama - EUS-guided FNA in combination with flow cytometry diagnosed lymphoma

University of Alabama - Researchers describe findings in HIV/AIDS vaccines studies

University of Alabama - Stem-like cells are identified for the corneal endothelium

University of Auckland - Information sought by callers to immunization hotline is discussed

University of Bari - Recent findings in diagnostics described

University of Basel Hospital - Three-dimensional perfusion culture reproducibly generates bone tissue

University of Birmingham - Findings in statins provide new insights

University of Bonn - Blood glucose levels in diabetic youth should be measured frequently

University of Bristol & North Bristol - Moxifloxacin has variable pharmacodynamics against anaerobic and aerobic pathogens

University of British Columbia, London - Cost-effectiveness of hormonal therapies in advanced breast cancer analyzed

University of California, Berkeley - Chytridiomycosis may be a novel pathogen being spread worldwide by carriers

University of California, Davis - Rare case of secondary transitional cell carcinoma reported

University of California, Los Angeles - Anthracyclines inhibited 26S proteasome and P-glycoprotein

University of California, San Diego - Altered axonal architecture slows amyotrophic lateral sclerosis

University of California, San Francisco - HAART is not associated with reduced anal intraepithelial neoplasia prevalence

University of California, San Francisco - HIV prevention case management facilitates healthy behavior after incarceration

University of California, San Francisco - Screening assay detects CD8+ cell noncytotoxic anti-HIV response

University of Chicago Children's Hospital - Intracardiac echocardiography suitable for use in perimembranous VSD closure

University of Cincinnati - Apoptosis modulates protective immunity to Histoplasma capsulatum

University of Cologne - Laparoscopic study reveals weight loss but high esophagitis incidence

University of Cologne - Nidogen ablation causes basement membrane defects and perinatal lethality

University of Colorado - Missed opportunities lead to low influenza immunization rates among children

University of Copenhagen - LapSim virtual reality system suitable for use in laparoscopic surgery training

University of Copenhagen - Neonatal vitamin K treatment can lower risk of adult alcohol dependence

University of Dusseldorf - Physical activity powers antioxidant and antiatherogenic activity

University of Essen - Basal ganglia infarction mimicked as glioblastoma

University of Florida - Anti-huntingtin shRNAs induce partial reversal of Huntington disease

University of Freiburg Hospital - Titanium-reinforced ceramic implant abutments more durable than all-ceramic abutments

University of Gothenburg - Survivors of lymphoblastic leukemia have higher total body fat and poor lipid profile

University of Halle Wittenberg - Brassicaceae AvrBs3-like effectors are involved in virulence

University of Heidelberg - Acyclovir therapy does not prevent recurrent post-transplantation hepatitis

University of Helsinki - HHV-6 and HHV-7 reactivations following pediatric SCT correlate with clinical symptoms

University of Iowa - Disease-related tau modifications influence tau-Fyn interaction

University of Iowa Hospital & Clinic - Canal wall reconstruction tympanomastoidectomy with mastoid obliteration effective for cholesteatoma

University of Jena - Self-management program can improve glycemic control without impaired hypoglycemic risk

University of Kuopio - Children of type 2 diabetics with the haplotype PPARGC1A are at increased risk for diabetes

University of Kuopio - VP22 does not significantly enhance enzyme prodrug cancer gene therapy

University of Lancaster - Study of polymorphism recombination reveals multiple hotspots in human genes

University of Lausanne - Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

University of Laval, Quebec - Haplotypes in PLTP gene are associated with obesity-related phenotypes

University of Leeds - Cyclooxygenase-2 inhibition therapy assessed for use in chemoprevention

University of Leipzig - Molecular pathways should be considered when choosing hormone replacement regimen

University of Limburg, Maastricht - Low birth weight influences creatinine clearance in young adults

University of London Imperial College - Chronic fatigue syndrome is associated with human leukocyte antigen alleles

University of Louisville - Findings advance knowledge in obesity pathogenesis research

University of Louisville - Intraspinal application of endothelin results in focal ischemic injury of spinal gray matter

University of Manchester - New biotech company developing antibacterial compounds wins Bionow award

University of Maryland - Hypoxia-inducible factor 1 mediates estrogen-induced stimulation of VEGF

University of Massachusetts - Blood volume changes reflect tumor response to antiangiogenic therapy

University of Melbourne - Researchers publish new studies and findings in the area of breast cancer

University of Michigan -  Helicobacter pylori outer membrane protein induces dendritic cell maturation

University of Michigan Medical Center - Pioglitazone protects obese, insulin resistant mice against arterial thrombosis

University of Milan - HIV-1-PR inhibitors are identified that do not create resistance

University of Minnesota - Duplication of Down syndrome critical region does not predict facial phenotype

University of Nebraska Medical Center - Stress ^99mTc-tetrofosmin myocardial perfusion imaging is linked to higher mortality

University of New South Wales - Acetylglucosamine pyrophosphorylase of Giardia intestinalis is characterized

University of North Carolina - Fibrosis after liver transplantation involves hepatic stellate cell activation

University of Occupational & Environmental Health, Fukuoka - Relevance of Delta Np63 expression in prognosticating lung cancer not supported

University of Oklahoma Health Sciences Center - No evidence found supporting HPV-negative LSIL as cervical cancer risk factor

University of Oslo - Techniques developed to detect minimal residual disease in neuroblastoma patients

University of Oxford - CD8 cell epitope-flanking mutations disrupt proteasomal processing of HIV-1 Nef

University of Oxford - Research in HIV/AIDS pathogenesis provides new insights

University of Paris 07 - New findings in the area of HIV/AIDS pathogenesis detailed

University of Parma - Endometrial carcinoma is not accurately predicted by transvaginal ultrasound

University of Pavia - Free flaps superior to pedicled flaps for reconstruction after tumor recurrence

University of Pennsylvania - CNS neoplasms graded using continuous arterial spin labeled perfusion

University of Pennsylvania - Conditional lethality yields new vaccine strain of Listeria monocytogenes

University of Pennsylvania - Studies advance knowledge in virology research

University of Queensland, Brisbane - Obesity is linked to increased CV risk and proteinuria progression in transplant patients

University of Reading - Aluminium, a component of antiperspirants, implicated in breast cancer

University of Shizuoka - Poly(methyl methacrylate) microchip limits uncontrolled analyte adsorption

University of South Carolina -  Plasmodium falciparum displays varying gene expression patterns in life

University of Southern California - Genetic factors play important role in chemoprotective action of green tea

University of Sydney - Evidence of response shift and response restriction in patients with advanced cancer analyzed

University of Sydney - Link between myocardial perfusion SPECT and severe CAD is modified by LVH and diabetes

University of Texas Medical Branch, Galveston - Researchers' findings advance heart failure research

University of Toronto - Telomerase overexpression does not prevent telomere shortening in hematopoietic cells

University of Trieste - Antibodies that neutralize complement-regulatory proteins control resistance in cancer

University of Ulster - Behavioral risk factors leading to obesity are reviewed

University of Utrecht - Request for euthanasia linked to depression among terminally ill cancer patients

University of Victor Segalen, Bordeaux - Therapeutic education program increases HAART compliance

University of Virginia - Antiviral therapy and low-dose tricyclic antidepressants may help prevent postherpetic neuralgia

University of Virginia - Mastectomy rates in breast cancer patients are affected by patient distance to radiation therapy facilities

University of Virginia - Ultrasound interactions with microbubbles trigger new vessel growth in murine skeletal muscle

University of Washington - Black-white disparity in receipt of recommended colon cancer treatment observed

University of Washington - Nutrient density score helps develop healthy diet

University of West Indies, Kingston - Extraspinal osteoarticular tuberculosis often undiagnosed in nonendemic areas

University of Western Australia, Nedlands - Community-acquired MRSA strains have not been established in hospitals in Western Australia

University of Witten/Herdecke, Datteln - New findings in obesity and diabetes described

University of Zurich Hospital - Findings in diagnostics provide new insights

University of Zurich Hospital - Recent findings illuminate research in oncology

Uppsala University - Fatty acid composition of serum lipids predicts development of metabolic syndrome in men

VA Medical Center, Milwaukee - Morbidly obese patients respond equally to desflurane or sevoflurane when concentration is controlled

Verispan - Studies show constant measurement is key to pharmaceutical sampling programs

Vi-Jon Laboratories, Inc. - U.S. FDA recognizes alcohol-based hand sanitizers as safe and effective for consumer use

Vision-Sciences, Inc. - Maker of endoscopic devices reports second quarter sales increase of 13%

Vital Images, Inc. - Imaging software company reports third quarter revenue up 42% over year ago

Vital Therapies, Inc. - Liver assist device maker completes first closing of $8M private financing

Vrije University of Amsterdam - High stem cell frequency in AML at diagnosis predicts high minimal residual disease and poor survival

Vrije University of Amsterdam - Virus-mediated metalloproteinase inhibition does not alter antitumor efficacy

Wayne State University, Detroit - New research in the area of obstetrics detailed

Weill Medical College of Cornell University, New York - Researchers provide details of new studies and findings in the area of statins

Weizmann Institute of Science, Rehovot - Human CTL epitopes may be candidates for prostate cancer immunotherapy

Wesley Hospital, Brisbane - Researchers' data advance obesity surgery research

West Virginia University - Signaling cascades may contribute to chemotherapy-induced alterations of marrow microenvironment

Westaim Corporation - Technology investor announces plans to pursue IPO for Nucryst Pharmaceuticals

Western Galilee Hospital, Nahariyya - New research in the area of hemodialysis detailed

Wholefood Farmacy Corp. - Health and wellness company dismissed from pending litigation

Windrose Medical Properties Trust - Medical properties group acquires interest in office building for $4.9 million

Wistar Institute of Anatomy & Biology, Philadelphia - Mechanisms of ATM signaling reviewed

Yale University - Childhood obesity has long-term impacts on cardiovascular and general health

Yale University - Multilevel ProDisc lumbar total disc arthroplasty safe and effective

Yale University - Suppressor T cells are induced through epicutaneous immunization

Yonsei University, Seoul - Vaccine protects Nepalese children against Japanese encephalitis

Zhejiang University - Bik/NBK accumulation correlates with apoptosis induction by proteasome inhibitors

Zhejiang University School of Medicine, Suhl - Hyperviscosity in obese school children is related to subclinical atherosclerosis

ZymoGenetics, Inc. - Company developing therapeutic proteins reports net loss of $20.4 million

enGene Inc. - Research award presented for protein therapeutics system for diabetes

sanofi-aventis Group - Study shows Alvesco for asthma has low incidence of oropharyngeal side effects