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U.S. National Cancer Institute

Estrogens play important role in early pathologic process towards breast cancer

Published in Medicine and Law Weekly, December 9th, 2005

Estrogens play an important role in the early pathologic process towards breast cancer.

Researchers in the United States "sought to determine whether serum concentrations of estrogens, androgens, and sex hormone binding globulin in postmenopausal women were related to the presence of mammary hyperplasia, an established breast cancer risk factor."

"Study participants provided serum before breast biopsy or mastectomy in three hospitals in Grand Rapids, Michigan, between 1977 and 1987. A total of 179 subjects with breast hyperplasia were compared with 152 subjects with nonproliferative breast changes that are not associated with increased breast cancer...

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