Published in Medicine and Law Weekly, December 30th, 2005
"Mutations in Plasmodium falciparum dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) genes have been used as means to predict treatment failure to sulfadoxine-pyrimethamine (SP) and for monitoring/surveillance of resistance to the drug in many areas where malaria is endemic.
"However, patients responses to treatment are significantly dependent on factors like host immunity profile of treated patients," scientists...
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