University of Barcelona
New findings in the area of adipose tissue described
Published in Medicine and Law Weekly, April 21st, 2006
Study 1: PPARalpha regulates the limiting step in the oxidation of fatty acids in liver mitochondria.
According to recent research from Spain, "The liver plays a central role in the response to fasting. The hormonal profile in this condition, low insulin, and high concentrations of glucagon in plasma, induce the release of large amounts of fatty acids from adipose tissue. Prolonged starvation can therefore induce a dramatic change in the fatty acid oxidative capacity of liver metabolism. Modulation of gene expression by PPARalpha plays a crucial role in this response."
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