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Oklahoma State University

 Mannheimia haemolytica protein enhances vaccine efficacy

Published in Medicine and Law Weekly, May 26th, 2006

Recombinant Mannheimia haemolytica serotype 1 outer membrane protein PlpE enhances commercial M. haemolytica vaccine-induced resistance against serotype 6 challenge.

According to recent research from the United States, "Mannheimia haemolytica outer membrane protein P1pE, a major immunogenic outer membrane lipoprotein has identical sequences in serotypes 1 (S1) and S6. Recombinant outer membrane lipoprotein PlpE (rPLpE) from M. haemolytica S1 was added to commercial M. haemolytica S1 vaccines to determine if it would enhance vaccine-induced immunity against heterotypic M. haemolytica S6 challenge. Serum antibody responses to...

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