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Medicine & Law Weekly

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Alfred Hospital, Melbourne



Women with bipolar disorder treated with tamoxifen show significant symptom improvement



June 2nd, 2006

Women with bipolar disorder treated with tamoxifen show significant symptom improvement.

Scientists at the Alfred Hospital in Melbourne "tested and compared the use of two adjunctive hormonal agents, tamoxifen and medroxyprogesterone acetate (MPA), for the treatment of acute mania or hypomania."

"A total of 13 women with acute Bipolar Affective Disorder in the manic or hypomanic phase were recruited from a clinical population to participate in this 28-day, three-arm, double blind, placebo-controlled study," explained J. Kulkarni and colleagues.

"The women who received tamoxifen exhibited significant improvement in symptoms of...


Source: Medicine & Law Weekly (2006-06-02)

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