Manchester Royal Infirmary
Findings from the United Kingdom, United States and Turkey in atherosclerosis provide new insights
Published in Medicine and Law Weekly, June 9th, 2006
Study 1: A semi-automated method has been developed for the determination of serum paraoxonase activity using paraoxon as substrate.
According to recent research from England, "Serum paraoxonase (PON1) is an enzyme associated with HDL, and its ability to protect LDL from oxidation is one mechanism by which HDL protects against atherosclerosis. Low concentrations of PON1 are found in patients with type 2 diabetes or coronary heart disease. Serum PON1 activity may also be important in avoidance of organophosphate toxicity in industry."
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