Osaka University
Liver cancer recurrence after resection correlates with angiogenic factors
Published in Medicine and Law Weekly, June 9th, 2006
According to a study from Japan, "Hepatocellular carcinoma (HCC) is a hypervascular tumor and angiogenesis plays an important role in its progression. Angiogenesis is regulated by a balance between pro- and antiangiogenic molecules."
"The aim of this study was to investigate the expressions of angiogenic factors and elucidate their roles in angiogenesis in HCC. We investigated immunohistochemical expression of vascular endothelial growth factor (VEGF), angiopoietins (Ang-1 and Ang-2), hypoxia-induced factor-1 alpha (HIF-1 alpha) and thrombospondin-1 (TSP-1) in 60 specimens of...
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