SW Foundation of Biomedical Research, U.S.
Hepatitis C virus response to interferon in chimpanzees is tissue specific
Published in Medicine and Law Weekly, July 7th, 2006
"The mechanism of the interferon-alpha (IFN-alpha)-induced antiviral response during hepatitis C virus (HCV) therapy is not completely understood. In this study, we examined the transcriptional response to IFN-alpha in uninfected chimpanzees after single doses of chimpanzee, human, or human-pegylated IFN-alpha," wrote R.E. Lanford and colleagues, SW Foundation of Biomedical Research.
"Liver and peripheral blood mononuclear cell (PBMC) samples were used for total genome microarray analysis....
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