Published in Medicine and Law Weekly, August 4th, 2006
According to recent research published in the journal Cancer Research, "The transforming growth factor-beta superfamily member activin and its antagonist, follistatin, act as a pleiotropic growth factor system that controls cell proliferation, differentiation, and apoptosis. Activin inhibits fibroblast growth factor 2-induced sprouting angiogenesis in vitro (spheroidal angiogenesis assay) and in vivo (Matrigel assay)."
"To further study the role of the activin/follistatin system during angiogenesis and tumor progression, activin- and...
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