Shanghai Research Institute of Hypertension, People's Republic of China
Ischemic diseases may be treated by using fibrin to stimulate therapeutic angiogenesis
Published in Medicine and Law Weekly, August 25th, 2006
"Fibrin gel has been used as a carrier of angiogenic molecules to promote neovascularization in animal models of limb ischaemia," scientists writing in the journal Clinical and Experimental Pharmacology and Physiology report.
"However," wrote C.L. Fan and colleagues, Shanghai Research Institute of Hypertension, "little is known about the effects of fibrin itself under such pathological conditions. Accordingly, the present study tested the efficacy of fibrin in a rabbit model of acute hindlimb ischaemia. Unilateral ischaemia was induced by resection of the...
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