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European Institute of Oncology, Italy

Pulmonary hamartoma development related to sex steroid hormone receptor expression

Published in Medicine and Law Weekly, September 8th, 2006

Pulmonary hamartoma development and growth might be related to sex steroid hormone receptor expression.

"Sex steroid hormone [i.e., estrogen (ER), progesterone (PgR), and androgen (AR)] receptors have been identified previously in normal salivary glands and, more variably, in salivary gland and salivary gland-type tumors. No data are available, however, on their expression in pulmonary hamartoma, a benign biphasic tumor consisting of reactive epithelial cells and neoplastic fibromyxoid stroma, cartilage and fat, which shares some morphologic, immunophenotypic, and genotypic features to pleomorphic adenoma of major salivary glands," scientists in Italy reported.

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