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Researchers' work from the United States adds to diabetes body of knowledge
October 13th, 2006
Diabetes data are the focus of recent research from the United States. Study 1: Small molecule-mediated activation of AMP-activated protein kinase offers a promising approach for the treatment of type 2 diabetes. According to recent research from the United States, "AMP-activated protein kinase (AMPK) is a key sensor and regulator of intracellular and whole-body energy metabolism. We have identified a thienopyridone family of AMPK activators." "A-769662 directly stimulated partially purified rat liver AMPK (EC50=0.8 mcM) and inhibited fatty acid synthesis in primary rat hepatocytes (IC50 =3.2 mcM). Short-term treatment...
Source: Medicine & Law Weekly (2006-10-13)
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