University of Hawaii, U.S.
Studies from the United States and Sweden add new findings to vectors body of knowledge
Published in Medicine and Law Weekly, October 13th, 2006
Study 1: HIV-based defective lentiviral vectors effectively transduce primary mouse blood- and bone marrow-derived monocytes/macrophages.
According to scientists in the United States, "Human immunodeficiency virus type 1-based defective lentiviral vectors (HIV-based vector) efficiently transduce a wide range of mammalian cell types, but little is known with respect to their utility for gene transfer applications involving primary mouse monocytes and macrophages. This may be important for preclinical development of a range of potential gene therapeutic modalities."
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