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American Association for Cancer Research
Potential diagnostic marker indicates the effectiveness of anti-angiogenic drugs
October 13th, 2006
If an anti-angiogenic drug is successfully starving a cancer patient's tumor to death, the number of endothelial cells circulating in the individual's bloodstream will decrease, thus providing a potential biomarker for gauging the medication's effectiveness, according to U.S. National Cancer Institute (NCI) research. Previous studies have shown that the blood circulation of cancer patients has an abnormally high number of endothelial cells, which help construct blood vessels including those that feed the cancerous tumor. "For a cancer to survive, grow and spread, a tumor needs to make more endothelial cells and construct new blood vessels to provide...
Source: Medicine & Law Weekly (2006-10-13)
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