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Albert Einstein College of Medicine, U.S.
Research from the United States add new data to angiology body of knowledge
October 13th, 2006
New findings from the United States describe advances in angiology. Study 1: Caveolin-1-deficient aortic smooth muscle cells show cell-autonomous abnormalities in proliferation, migration, and endothelin-based signal transduction. Investigators working in the United States report, "We previously showed that ablation of caveolin-1 (Cav-1) gene expression in mice promotes neointimal hyperplasia in vivo, a phenomenon normally characterized by smooth muscle cell (SMC) migration and proliferation. Whether these defects are cell autonomous, i.e., due to loss of Cav-1 within SMCs or loss of Cav-1 expression in other adjacent cell types in vivo, remains...
Source: Medicine & Law Weekly (2006-10-13)
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