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Thrombocytopenic Purpura

GSK initiates repeat dosing study of its novel oral platelet growth factor, eltrombopag, in ITP

Published in Medicine and Law Weekly, May 4th, 2007

GlaxoSmithKline plc today announced the initiation of a global, open-label, single group trial that will assess the efficacy, safety and tolerability of eltrombopag in patients previously treated for chronic idiopathic thrombocytopenic purpura (ITP). The trial, called REPEAT (Repeat ExPosure to Eltrombopag in Adults with Idiopathic Thrombocytopenic Purpura) will evaluate a repeated dosing schedule of three six week cycles of eltrombopag treatment in 50 patients with chronic ITP who will be enrolled at multiple centres.

"The current treatment approaches to acutely increase the platelet count typically include treatment with steroids or IV gammaglobulin - both of which...

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