Clinical Trial Research
PPD Completes First-in-Human Trial for Novel Statin
Published in Medicine and Law Weekly, August 3rd, 2007
The recently completed Phase I trial was a randomized, placebo-controlled evaluation in healthy subjects to investigate the safety, tolerability and pharmacokinetics of single rising oral doses of PPD's statin. The study enrolled 36 male subjects. The compound was studied across a broad range of doses in this trial and was safe and well tolerated at all dosage levels. In addition, blood levels of the compound measured during the trial...
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