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Diabetes Therapy

Research reports on diabetes therapy from Hannover Medical School, Department of Gastroenterology provide new insights

Published in Medicine and Law Weekly, April 18th, 2008

A new study, 'Role of regulatory T cells for the treatment of type 1 diabetes mellitus,' is now available. According to recent research published in the journal Hormone and Metabolic Research, "Beta-cell specific autoreactive T cells can be found in patients with type I diabetes (T1D) and in healthy controls. They are usually controlled by a network of regulatory mechanisms including CD4+CD25+Foxp3+ regulatory T cells (Tregs)."

"It was suspected that defects in Treg number and activity are causally related to the development of T1D. Although there are hints that this concept might be true, it is neither proven in animal models nor in patients with T1D. However,...

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