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Proteinuria

Research on proteinuria discussed by P. Ruggenenti and co-researchers

Published in Medicine and Law Weekly, July 18th, 2008

"Heavy proteinuria is a major determinant of progression to ESRD for patients with chronic nephropathies and reducing proteinuria should be a key target for renoprotective therapy. In the Remission Clinic, we applied a multimodal intervention to target urinary proteins in 56 consecutive patients who had >3 g proteinuria/d despite angiotensin-converting enzyme inhibitor therapy," scientists writing in the Journal of the American Society of Nephrology report.

"We compared the rate of GFR decline and incidence of ESRD in this cohort with 56 matched historical reference subjects who had received conventional therapy titrated to a target BP. During a median...

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