Published in Medicine and Law Weekly, March 27th, 2009
"We investigated the local applicability and Safety of tacrolimus for distal colitis. Patients; with refractory left-sided colitis or proctitis were treated for 4 weeks with a daily tacrolimus 2-4 mg enema or 2 mg suppository. Safety of local tacrolimus treatment was assessed by measurement of whole blood tacrolimus trough levels by monitoring liver and kidney function and blood glucose levels. Efficacy of treatment was assessed...
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