Pharmacokinetics

Study findings on pharmacokinetics are outlined in reports from University of Queensland

Published in Medicine and Law Weekly, April 24th, 2009

According to recent research from Brisbane, Australia, " Tc-99m-DI-DD3B6/22-80B3 (ThromboView (R), hereafter abbreviated to Tc-99m-DI-80B3 Fab') is a radio-labelled humanised monoclonal Fab' fragment with affinity and specificity for D-dimer domains of cross-linked fibrin. Detection of thromboembolic events has been demonstrated in canine models."

"The study objectives were evaluation of safety and characterisation of biodistribution, immunogenicity and pharmacokinetic profile of increasing doses of Tc-99m-DI-80B3 Fab' in subjects with acute lower-limb DVT. Twenty-six patients with acute lower limb DVT were enrolled. Of these, 21 received a single intravenous dose of...

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Source: Medicine and Law Weekly (2009-04-24)

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