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Asthma

Reports from University Medical Center describe recent advances in asthma

Published in Medicine and Law Weekly, February 12th, 2010

"Long-acting beta(2)-agonists are an established controller medication in asthma. BI 1744 is a novel L/long-acting beta(2)-agonist with a preclinical profile that suggests 24-hour bronchodilation and bronchoprotection may be achieved," researchers in Hamilton, Canada report.

"To examine the bronchoprotective effects of single doses of BI 1744 against methacholine provocation in subjects with mild asthma. Thirty-one subjects with mild asthma were randomized to receive single doses of BI 1744 (2, 5, 10, 20 mu g) or placebo on separate days according to a double-blind, 5-way crossover design. Methacholine challenges were performed at 30 minutes and at 4, 8, 24, and 32...

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